Megan Null

Biographic Data

ID9064129
NAMEMegan Null
GIVEN NAMESMegan
SIGNATURENULL M
AFFILIATIONSUniversity of Virginia
ORCID0009-0001-9584-4606
VERIFIEDYes
TOTAL WORKS2
TOTAL CITATIONS0
WORKS AS AUTHOR2
WORKS AS EDITOR0
FIRST PUBLICATION YEAR2024
LATEST PUBLICATION YEAR2025
H-INDEX0

  • A narrative review of the pathophysiology of sepsis in sub-Saharan Africa

    Open AccessPhoebe Gruccio, William S Girard et al.ARTICLEPLOS Global Public Health2025

    Sepsis remains a significant global health threat with a disproportionate burden in low-income countries including those in sub-Saharan Africa where case fatality rates are as high as 30% to 50%. Defined as a severe systemic response to infection, sepsis leads to widespread immune dysregulation and organ dysfunction, including adrenal insufficiency. Critical illness-related corticosteroid insufficiency (CIRCI) arises from dysregulation of the hyp…

  • The Universal Vital Assessment (UVA) score at 6 hours post-resuscitation predicts mortality in hospitalized adults with severe sepsis in Mbarara, Uganda

    Open AccessMegan Null, Mark R Conaway et al.ARTICLEPLOS Global Public Health2024

    Sepsis is the leading cause of global death with the highest burden found in sub-Saharan Africa (sSA). The Universal Vital Assessment (UVA) score is a validated resource-appropriate clinical tool to identify hospitalized patients in sSA who are at risk of in-hospital mortality. Whether a decrease in the UVA score over 6 hours of resuscitation from sepsis is associated with improved outcomes is unknown. We aimed to determine (1) the association be…