Sepiso K Masenga

Biographic Data

ID9064337
NAMESepiso K Masenga
GIVEN NAMESSepiso K
FAMILY NAMEMasenga
SIGNATUREMASENGA S K
AFFILIATIONSMulungushi University
ORCID0000-0003-4376-5831
VERIFIEDYes
TOTAL WORKS11
TOTAL CITATIONS0
AUTHOR COUNT11
EDITOR COUNT0
FIRST PUBLICATION YEAR2023
LATEST PUBLICATION YEAR2026
H-INDEX0

  • Correlates of Ki-67 proliferation index in a cohort of women with suspected breast cancer in Lusaka, Zambia

    Open AccessJoaquim Musamba, David Chisompola et al.ARTICLEPLOS Global Public Health2026

    Ki-67 is a key biomarker of tumor proliferation in breast cancer, yet its clinical correlates in this population, where disease is often detected at earlier stages, remain underexplored. This study aimed to identify factors independently associated with high Ki-67 expression among women investigated for suspected breast cancer at Unilabs Laboratory, Lusaka, Zambia. A retrospective cross-sectional analysis was conducted on 208 women suspected of h…

  • Determinants of left ventricular hypertrophy in a cohort attending a medical clinic

    Open AccessSydney Mulamfu, David Chisompola et al.ARTICLEPLOS Global Public Health2026

    Left ventricular hypertrophy (LVH) is a significant cardiovascular complication in sub-Saharan Africa. However, sex-specific determinants of LVH in this population remain poorly understood. This study aimed to identify factors associated with LVH in a cohort attending medical clinic, stratified by sex. We conducted a cross-sectional analysis of 333 adults attending an outpatient clinic at Livingstone Teaching Hospital, Zambia. LVH was diagnosed b…

  • Incidence and correlates of chronic anemia in people living with HIV Initiating ART

    Open AccessKingsley Kamvuma, Benson M Hamooya et al.ARTICLEPLOS Global Public Health2026

    Chronic anemia remains a common and clinically important complication among people living with HIV (PLWH) receiving antiretroviral therapy (ART), contributing to increased morbidity and mortality, particularly in persistent or severe cases. This study estimated the incidence and correlates of chronic anemia among PLWH initiating ART in Zambia. A five-year retrospective cohort study was conducted among 243 adults who initiated ART between February…

  • Metabolic and inflammatory axes of insulin resistance in normoglycemic adults with high HIV burden

    Open AccessSitumbeko Liweleya, Brian Halubanza et al.ARTICLEPLOS Global Public Health2026

    Insulin resistance (IR) precedes type 2 diabetes and drives cardiovascular risk, but its early features in normoglycemic individuals remain unclear. The main goal of the study was to characterize multifactorial determinants of IR in normoglycemic adults. We conducted a retrospective cross-sectional analysis of a census of 100 normoglycemic adults (median age 44 years, interquartile range (IQR): 35–49), 70% (70/100) of whom were living with HIV an…

  • Prevalence and factors associated with illicit substance use among persons with Schizophrenia at a Tertiary Referral Hospital in Zambia

    Open AccessKimberley R Kurehwatira, Emmanuel L Luwaya et al.ARTICLEPLOS Global Public Health2026

    Schizophrenia frequently involves comorbid substance use, exacerbating symptoms and reducing treatment efficacy yet no prior studies have examined this comorbidity locally. This study determined the prevalence and factors associated with illicit substance use among adults with schizophrenia at the Livingstone University Teaching Hospital (LUTH). A hospital-based single center cross-sectional study was conducted at LUTH from January to June 2023. …

  • Sex differences in severe acute malnutrition in children under 5 years in Zambia

    Open AccessGift C Chama, Situmbeko Liweleya et al.ARTICLEPLOS Global Public Health2025

    Severe acute malnutrition (SAM) is a critical public health issue, particularly in low and middle-income countries like Zambia, where it significantly contributes to under-five mortality. While general factors associated with SAM, including its overall burden, are well documented, the role of sex differences in correlates of SAM has not been thoroughly explored. Hence, this study aimed to examine sex differences in correlates of SAM by identifyin…

  • Hypertensive crisis

    Open AccessLukundo Siame, Mbulazi B Kabeta et al.ARTICLEPLOS Global Public Health2025

    BACKGROUND: Hypertensive crisis, including hypertensive emergency (with target organ damage) and hypertensive urgency (without target organ damage), is a critical public health condition at Livingstone University Teaching Hospital (LUTH). Hypertensive crisis has been linked to severe complications, including stroke, renal failure, and heart disease, leading to increased mortality, morbidity, and healthcare costs due to intensive treatment, prolon…

  • Reducing mortality in acute kidney disease through comprehensive laboratory support

    Open AccessSepiso K Masenga, Luyando Mutelo et al.ARTICLEPLOS Global Public Health2025

    Acute kidney disease (AKD) contributes significantly to morbidity and mortality, particularly in low-resource settings where limited diagnostic capacity often leads to delayed recognition and suboptimal management. We aimed to evaluate the impact of implementing a comprehensive patient-specific clinical laboratory support on clinical outcomes in AKD and to identify factors associated with mortality. We conducted a mixed-method hybrid type 3 imple…

  • Prevalence and risk factors of birth asphyxia at Livingstone University teaching hospital

    Open AccessNestorine N Ngongo, Patson Sichamba et al.ARTICLEPLOS Global Public Health2025

    Birth asphyxia remains a leading cause of neonatal mortality in low-resource settings, with Zambia reporting a rate of 24 deaths per 1,000 live births. Birth asphyxia accounts for over 20% of neonatal ICU admissions. This study aimed to determine its prevalence and risk factors to inform targeted interventions. We conducted a secondary data analysis of medical records at Livingstone University Teaching Hospital, Zambia, including 497 maternal–neo…

  • Tuberculosis-related deaths at a tertiary hospital in Zambia

    Open AccessLukundo Siame, Eemmanuel Chembe et al.ARTICLEPLOS Global Public Health2024

    Tuberculosis (TB) mortality remains a significant public health concern globally. This study aimed to determine the prevalence of tuberculosis-related deaths and associated factors among patients at Livingstone University Teaching Hospital (LUTH) Chest Clinic, Zambia. We conducted a retrospective cross-sectional study among 694 individuals (507 adult and 187 children) diagnosed with drug susceptible TB disease between January 1, 2021, and Decembe…

  • HIV test-and-treat policy improves clinical outcomes in Zambian adults from Southern Province

    Open AccessBenson M Hamooya, Simon Mutembo et al.ARTICLEFrontiers in Public Health2023

    Background Globally, most countries have implemented a test-and-treat policy to reduce morbidity and mortality associated with HIV infection. However, the impact of this strategy has not been critically appraised in many settings, including Zambia. We evaluated the retention and clinical outcomes of adults enrolled in antiretroviral therapy (ART) and assessed the impact of the test-and-treat policy. Methods We conducted a retrospective cohort stu…