Determinants of left ventricular hypertrophy in a cohort attending a medical clinic

A comparative analysis stratified by sex

Bibliographic Data

ID19593775
AuthorsSydney Mulamfu (Mulungushi University), David Chisompola (0000-0002-3765-0635, Mulungushi University, corresponding author), Martin Chakulya (Mulungushi University), John Nzobokela (Mulungushi University), Phinnoty Mwansa (0009-0004-9244-7287, Mulungushi University), Benson M Hamooya (0000-0003-1385-0998, Livingstone Hospital), Joreen P Povia (0009-0006-7438-1549, Livingstone College), Sepiso K Masenga (0000-0003-4376-5831, Mulungushi University, corresponding author)
EditorsZulkarnain Jaafar
Year2026
Volume6
Issue5
Pagese0006382
Publication date2026-05-12
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0006382
PMID42118761
OpenAlexW7160951036
LanguageEN
References cited29

Left ventricular hypertrophy (LVH) is a significant cardiovascular complication in sub-Saharan Africa. However, sex-specific determinants of LVH in this population remain poorly understood. This study aimed to identify factors associated with LVH in a cohort attending medical clinic, stratified by sex. We conducted a cross-sectional analysis of 333 adults attending an outpatient clinic at Livingstone Teaching Hospital, Zambia. LVH was diagnosed by echocardiography. Data on demographics, clinical history (HIV, TB, hypertension) and metabolic profiles were collected. Univariable and multivariable logistic regression models were used to identify predictors of LVH in the overall cohort and in sex-stratified subgroups. p

Cohort · Cohort study · Heart failure · Left ventricular hypertrophy · Logistic regression · Outpatient clinic · Population · Waist · Blood Pressure and Hypertension Studies · Diabetes, Cardiovascular Risks, and Lipoproteins · Global Health and Epidemiology

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