EO Agbaje
Biographic Data
| ID | 9274512 |
|---|---|
| NAME | EO Agbaje |
| GIVEN NAMES | EO |
| FAMILY NAME | Agbaje |
| SIGNATURE | AGBAJE E |
| AFFILIATIONS | University of Lagos |
| VERIFIED | No |
| TOTAL WORKS | 3 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 3 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2010 |
| LATEST PUBLICATION YEAR | 2013 |
| H-INDEX | 0 |
Antihyperglycemic profile of erinidine isolated from Hunteria umbellate seed
Water decoction made from the seed of Hunteria umbellata is widely used in the traditional management of diabetes mellitus by Nigerian herbalists, particularly, in the southwest region of the country. Recently, a new bisindole alkaloid, erinidine, was isolated but its antihyperglycemic profile remains largely un-investigated scientifically. This forms the basis for the current study which is primarily designed at investigating the antihyperglycem…
The Novel Antihyperglycaemic Action of Hunteria umbellate Seed Fractions Mediated Via Intestinal Glucose Uptake Inhibition
The present study evaluated the antihyperglycaemic effect and mechanism of action of fractions of the aqueous seed extract of Hunteria umbellata (K. Schum.) Hallier f. (HU) in normal and alloxan-induced hyperglycaemic rats. HU was partitioned in chloroform, acetyl acetate and butan-1-ol to give chloroform fraction (HU c), ethyl acetate fraction (HU e), butanol fraction (HU b) and the "residue" (HU m), respectively. 200 mg/kg of each of these frac…
Evaluation of the toxicity and reversibility profile of the aqueous seed extract of Hunteria umbellata (K.Schum) Hallier F. in rodents
Hunteria umbellata (K. Schum.) Hallier f. (family: Apocynaceae) is reputed for the folkloric management of labour, pain and swellings, stomach ulcers, diabetes, obesity, and anaemia, with no scientific report of its toxicity and reversibility profile. The present study was, therefore, aimed at investigating the in vivo toxicity and reversibility profile of the aqueous seed extract of Hunteria umbellata (HU). The acute oral and intraperitoneal tox…
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Evaluation of the toxicity and reversibility profile of the aqueous seed extract of Hunteria umbellata (K.Schum) Hallier F. in rodents
Hunteria umbellata (K. Schum.) Hallier f. (family: Apocynaceae) is reputed for the folkloric management of labour, pain and swellings, stomach ulcers, diabetes, obesity, and anaemia, with no scientific report of its toxicity and reversibility profile. The present study was, therefore, aimed at investigating the in vivo toxicity and reversibility profile of the aqueous seed extract of Hunteria umbellata (HU). The acute oral and intraperitoneal tox…
The Novel Antihyperglycaemic Action of Hunteria umbellate Seed Fractions Mediated Via Intestinal Glucose Uptake Inhibition
The present study evaluated the antihyperglycaemic effect and mechanism of action of fractions of the aqueous seed extract of Hunteria umbellata (K. Schum.) Hallier f. (HU) in normal and alloxan-induced hyperglycaemic rats. HU was partitioned in chloroform, acetyl acetate and butan-1-ol to give chloroform fraction (HU c), ethyl acetate fraction (HU e), butanol fraction (HU b) and the "residue" (HU m), respectively. 200 mg/kg of each of these frac…
Antihyperglycemic profile of erinidine isolated from Hunteria umbellate seed
Water decoction made from the seed of Hunteria umbellata is widely used in the traditional management of diabetes mellitus by Nigerian herbalists, particularly, in the southwest region of the country. Recently, a new bisindole alkaloid, erinidine, was isolated but its antihyperglycemic profile remains largely un-investigated scientifically. This forms the basis for the current study which is primarily designed at investigating the antihyperglycem…
Medicine (3 works) · Biochemistry (2 works) · Chemistry (2 works) · Internal Medicine (2 works) · Natural Antidiabetic Agents Studies (2 works) · Pharmacological Effects of Natural Compounds (2 works) · Pharmacology (2 works) · Abia (1 work) · Acute toxicity (1 work) · Aldose reductase (1 work)