Sandro L Bonatto
Biographic Data
| ID | 99201 |
|---|---|
| NAME | Sandro L Bonatto |
| GIVEN NAMES | Sandro L |
| FAMILY NAME | Bonatto |
| SIGNATURE | BONATTO S L |
| AFFILIATIONS | Pontifícia Universidade Católica do Rio Grande do Sul |
| ORCID | 0000-0002-0064-467X |
| VERIFIED | Yes |
| TOTAL WORKS | 18 |
| TOTAL CITATIONS | 100 |
| AUTHOR COUNT | 18 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1996 |
| LATEST PUBLICATION YEAR | 2019 |
| H-INDEX | 5 |
Phylogeographic evidence for two species of muriqui (genus Brachyteles )
The taxonomy of muriquis, the largest extant primates in the New World, is controversial. While some specialists argue for a monotypic genus ( Brachyteles arachnoides ), others favor a two‐species classification, splitting northern muriquis ( Brachyteles hypoxanthus ) from southern muriquis ( B. arachnoides ). This uncertainty affects how we study the differences between these highly endangered and charismatic primates, as well as the design of m…
Hybridization Between Neotropical Primates with Contrasting Sexual Dichromatism
Ancient remains and the first peopling of the A mericas: Reassessing the Hoyo Negro skull
OBJECTIVE: A noticeably well-preserved ∼12.500 years-old skeleton from the Hoyo Negro cave, Yucatán, México, was recently reported, along with its archaeological, genetic and skeletal characteristics. Based exclusively on an anatomical description of the skull (HN5/48), Chatters and colleagues stated that this specimen can be assigned to a set of ancient remains that differ from modern Native Americans, the so called "Paleoamericans". Here, we ai…
The population genetics of quechuas, the largest native south american group: Autosomal sequences, SNPs, and microsatellites evidence high level of diversity
Elucidating the pattern of genetic diversity for non‐European populations is necessary to make the benefits of human genetics research available to individuals from these groups. In the era of large human genomic initiatives, Native American populations have been neglected, in particular, the Quechua, the largest South Amerindian group settled along the Andes. We characterized the genetic diversity of a Quechua population in a global setting, usi…
Distribution of Y‐chromosome q lineages in native americans
Objectives: This investigation was performed to identify and evaluate the distribution of all 15 Y‐chromosome lineages belonging to the Q clade in a sample of natives from South America. Methods: One hundred and forty‐eight individuals from 20 Native American populations, as well as 24 Asian samples including Eskimos, were tested with 18 biallelic loci that can identify all currently known lineages of the Y‐Chromosome Q clade. Sequencing was perf…
A new subhaplogroup of native American Y-Chromosomes from the Andes
The human Y chromosome contains highly informative markers for making historical inferences about the pre-Columbian peopling of Americas. However, the scarcity of these markers has limited its use in the inference of shared ancestry and past migrations relevant to the origin of the culturally and biologically diverse Native Americans. To identify new single nucleotide polymorphisms (SNPs) and increase the phylogenetic resolution of the major hapl…
Mitochondrial Population Genomics Supports a Single Pre-Clovis Origin with a Coastal Route for the Peopling of the Americas
The peopling of America: Craniofacial shape variation on a continental scale and its interpretation from an interdisciplinary view
Twenty‐two years ago, Greenberg, Turner and Zegura ( Curr. Anthropol. 27,477–495, 1986) suggested a multidisciplinary model for the human settlement of the New World. Since their synthesis, several studies based mainly on partial evidence such as skull morphology and molecular genetics have presented competing, apparently mutually exclusive, settlement hypotheses. These contradictory views are represented by the genetic‐based Single Wave or Out o…
Phylogenetic information in polymorphic L1 and Alu insertions from East Asians and Native American populations
This study attempts to ascertain genetic affinities between Native American and East Asian populations by analyzing four polymorphic Alu insertions (PAIs) and three L1 polymorphic loci. These two genetic systems demonstrated strong congruence when levels of diversity and genetic distances were considered. Overall, genetic relatedness within Native American groups does not correlate with geographical and linguistic structure, although strong group…
Is haplogroup X present in extant South American Indians
A total of 1,159 mitochondrial DNA samples from two Mongolian, two Siberian, and 25 South Native American populations was surveyed for the presence of the C16278T mutation, frequently found in haplogroup X. Material from 25 carriers of that mutation was then sequenced for the hypervariable segment I (HVS-I) control region, and those that still were not classifiable in classical Amerindian haplogroups were further studied. The tests involved all t…
Human T-cell lymphotropic virus type II in Guaraní Indians, Southern Brazil
Human T-cell lymphotropic virus type II (HTLV-II) is found in many New World Indian groups on the American continent. In Brazil, HTLV-II has been found among urban residents and Indians in the Amazon region, in the North. Guaraní Indians in the South of Brazil were studied for HTLV-I/II infection. Among 52 individuals, three (5.76%) showed positive anti-HTLV-II antibodies (enzyme-linked immunosorbent assay and Western blot). This preliminary repo…
Mitochondrial DNA and Alu insertions in a genetically peculiar population: The Ayoreo Indians of Bolivia and Paraguay
A total of 91 Ayoreo individuals previously studied for blood groups and protein markers, living in two Bolivian and one Paraguayan communities, were extensively investigated in relation to the hypervariable 1 segment of the control and eight coding regions of their mitochondrial DNA (mtDNA). They show an extremely reduced mtDNA variability, the observed haplotypes being classifiable in just two haplogroups (C and D). They were also variously stu…
Short ReportExtremely limited mitochondrial DNA variability among the Aché Natives of Paraguay
The Aché present distinctive differences and reduced mtDNA HVS-1 variability compared to other South American Natives. Similar differences were observed for other genetic systems. At present it is not clear whether their peculiarities already existed in their founding populations or whether they were secondarily acquired due to a long period of isolation in the humid, subtropical forest
Intra- and Intercontinental Molecular Variability of an Alu Insertion in the 3' Untranslated Region of the LDLR Gene
One-hundred three individuals from two Mongolian, two Siberian, and ten native American populations were studied in relation to a 340-bp sequence from an Alu insertion located in the 3' untranslated region of the LDLR gene. Seven haplotypes have been determined, and haplotype B1 was the most common, accounting for about half the sequences found. In general, diversity values are quite high, about 2.5 times higher than those found in other autosoma…
Alu insertions versus blood group plus protein genetic variability in four Amerindian populations
The answer to the first question posed above is affirmative. However, the problem of whether the Aché derived from a Gê group that preceded the Guarani colonization of Paraguay, or are just a differentiated Guarani group, could not be answered with the genetic information available; the second hypothesis seems more likely at present, but the point to be emphasized is the striking genetic distinctiveness of the Aché as compared to other Amerindian…
Genetic, geographic, and linguistic variation among South American Indians: Possible sex influence
To better understand the relationship between genetic variability, geographical distance, and linguistic affiliation in South Amerinds, and to elucidate whether the migration rate is the same for both sexes, spatial autocorrelation, Mantel's test, and F ST analyses were performed in four sets of populations and alleles (group 1: 48 populations, 12 alleles; group 2: 16 (all belonging to the Tupi linguistic group) and 12; group 3: 21 and 17; and gr…
A single and early migration for the peopling of the Americas supported by mitochondrial DNA sequence data
To evaluate the number and time of the migration(s) that colonized the New World we analyzed all available sequences of the first hypervariable segment of the human mitochondrial DNA control region, including 544 Native Americans. Sequence and population trees showed that the Amerind, Na-Dene, and Eskimo are significantly closer among themselves than anyone is to Asian populations, with the exception of the Siberian Chukchi, that in some analyses…
Mitochondrial DNA polymorphism in three Brazilian Indian tribes
The first 360 base pairs of the mitochondrial DNA (mtDNA) major noncoding region from 82 individuals affiliated with the Brazilian Xavante, Zoró and Gavião tribes were sequenced. A total of 14 different lineages were observed, the largest number (8) being found among the Zoró. The latter share five lineages with the Gavião (who are their neighbors and are culturally similar to them), but only one with the Xavante. The lineages can be grouped into…
The peopling of America: Craniofacial shape variation on a continental scale and its interpretation from an interdisciplinary view
Twenty‐two years ago, Greenberg, Turner and Zegura ( Curr. Anthropol. 27,477–495, 1986) suggested a multidisciplinary model for the human settlement of the New World. Since their synthesis, several studies based mainly on partial evidence such as skull morphology and molecular genetics have presented competing, apparently mutually exclusive, settlement hypotheses. These contradictory views are represented by the genetic‐based Single Wave or Out o…
Genetic, geographic, and linguistic variation among South American Indians: Possible sex influence
To better understand the relationship between genetic variability, geographical distance, and linguistic affiliation in South Amerinds, and to elucidate whether the migration rate is the same for both sexes, spatial autocorrelation, Mantel's test, and F ST analyses were performed in four sets of populations and alleles (group 1: 48 populations, 12 alleles; group 2: 16 (all belonging to the Tupi linguistic group) and 12; group 3: 21 and 17; and gr…
Is haplogroup X present in extant South American Indians
A total of 1,159 mitochondrial DNA samples from two Mongolian, two Siberian, and 25 South Native American populations was surveyed for the presence of the C16278T mutation, frequently found in haplogroup X. Material from 25 carriers of that mutation was then sequenced for the hypervariable segment I (HVS-I) control region, and those that still were not classifiable in classical Amerindian haplogroups were further studied. The tests involved all t…
Hybridization Between Neotropical Primates with Contrasting Sexual Dichromatism
A new subhaplogroup of native American Y-Chromosomes from the Andes
The human Y chromosome contains highly informative markers for making historical inferences about the pre-Columbian peopling of Americas. However, the scarcity of these markers has limited its use in the inference of shared ancestry and past migrations relevant to the origin of the culturally and biologically diverse Native Americans. To identify new single nucleotide polymorphisms (SNPs) and increase the phylogenetic resolution of the major hapl…
Ancient remains and the first peopling of the A mericas: Reassessing the Hoyo Negro skull
OBJECTIVE: A noticeably well-preserved ∼12.500 years-old skeleton from the Hoyo Negro cave, Yucatán, México, was recently reported, along with its archaeological, genetic and skeletal characteristics. Based exclusively on an anatomical description of the skull (HN5/48), Chatters and colleagues stated that this specimen can be assigned to a set of ancient remains that differ from modern Native Americans, the so called "Paleoamericans". Here, we ai…
The population genetics of quechuas, the largest native south american group: Autosomal sequences, SNPs, and microsatellites evidence high level of diversity
Elucidating the pattern of genetic diversity for non‐European populations is necessary to make the benefits of human genetics research available to individuals from these groups. In the era of large human genomic initiatives, Native American populations have been neglected, in particular, the Quechua, the largest South Amerindian group settled along the Andes. We characterized the genetic diversity of a Quechua population in a global setting, usi…
Human T-cell lymphotropic virus type II in Guaraní Indians, Southern Brazil
Human T-cell lymphotropic virus type II (HTLV-II) is found in many New World Indian groups on the American continent. In Brazil, HTLV-II has been found among urban residents and Indians in the Amazon region, in the North. Guaraní Indians in the South of Brazil were studied for HTLV-I/II infection. Among 52 individuals, three (5.76%) showed positive anti-HTLV-II antibodies (enzyme-linked immunosorbent assay and Western blot). This preliminary repo…
Mitochondrial DNA polymorphism in three Brazilian Indian tribes
The first 360 base pairs of the mitochondrial DNA (mtDNA) major noncoding region from 82 individuals affiliated with the Brazilian Xavante, Zoró and Gavião tribes were sequenced. A total of 14 different lineages were observed, the largest number (8) being found among the Zoró. The latter share five lineages with the Gavião (who are their neighbors and are culturally similar to them), but only one with the Xavante. The lineages can be grouped into…
A single and early migration for the peopling of the Americas supported by mitochondrial DNA sequence data
To evaluate the number and time of the migration(s) that colonized the New World we analyzed all available sequences of the first hypervariable segment of the human mitochondrial DNA control region, including 544 Native Americans. Sequence and population trees showed that the Amerind, Na-Dene, and Eskimo are significantly closer among themselves than anyone is to Asian populations, with the exception of the Siberian Chukchi, that in some analyses…
Alu insertions versus blood group plus protein genetic variability in four Amerindian populations
The answer to the first question posed above is affirmative. However, the problem of whether the Aché derived from a Gê group that preceded the Guarani colonization of Paraguay, or are just a differentiated Guarani group, could not be answered with the genetic information available; the second hypothesis seems more likely at present, but the point to be emphasized is the striking genetic distinctiveness of the Aché as compared to other Amerindian…
Genetic, geographic, and linguistic variation among South American Indians: Possible sex influence
To better understand the relationship between genetic variability, geographical distance, and linguistic affiliation in South Amerinds, and to elucidate whether the migration rate is the same for both sexes, spatial autocorrelation, Mantel's test, and F ST analyses were performed in four sets of populations and alleles (group 1: 48 populations, 12 alleles; group 2: 16 (all belonging to the Tupi linguistic group) and 12; group 3: 21 and 17; and gr…
Mitochondrial DNA and Alu insertions in a genetically peculiar population: The Ayoreo Indians of Bolivia and Paraguay
A total of 91 Ayoreo individuals previously studied for blood groups and protein markers, living in two Bolivian and one Paraguayan communities, were extensively investigated in relation to the hypervariable 1 segment of the control and eight coding regions of their mitochondrial DNA (mtDNA). They show an extremely reduced mtDNA variability, the observed haplotypes being classifiable in just two haplogroups (C and D). They were also variously stu…
Short ReportExtremely limited mitochondrial DNA variability among the Aché Natives of Paraguay
The Aché present distinctive differences and reduced mtDNA HVS-1 variability compared to other South American Natives. Similar differences were observed for other genetic systems. At present it is not clear whether their peculiarities already existed in their founding populations or whether they were secondarily acquired due to a long period of isolation in the humid, subtropical forest
Intra- and Intercontinental Molecular Variability of an Alu Insertion in the 3' Untranslated Region of the LDLR Gene
One-hundred three individuals from two Mongolian, two Siberian, and ten native American populations were studied in relation to a 340-bp sequence from an Alu insertion located in the 3' untranslated region of the LDLR gene. Seven haplotypes have been determined, and haplotype B1 was the most common, accounting for about half the sequences found. In general, diversity values are quite high, about 2.5 times higher than those found in other autosoma…
Phylogenetic information in polymorphic L1 and Alu insertions from East Asians and Native American populations
This study attempts to ascertain genetic affinities between Native American and East Asian populations by analyzing four polymorphic Alu insertions (PAIs) and three L1 polymorphic loci. These two genetic systems demonstrated strong congruence when levels of diversity and genetic distances were considered. Overall, genetic relatedness within Native American groups does not correlate with geographical and linguistic structure, although strong group…
Is haplogroup X present in extant South American Indians
A total of 1,159 mitochondrial DNA samples from two Mongolian, two Siberian, and 25 South Native American populations was surveyed for the presence of the C16278T mutation, frequently found in haplogroup X. Material from 25 carriers of that mutation was then sequenced for the hypervariable segment I (HVS-I) control region, and those that still were not classifiable in classical Amerindian haplogroups were further studied. The tests involved all t…
Human T-cell lymphotropic virus type II in Guaraní Indians, Southern Brazil
Human T-cell lymphotropic virus type II (HTLV-II) is found in many New World Indian groups on the American continent. In Brazil, HTLV-II has been found among urban residents and Indians in the Amazon region, in the North. Guaraní Indians in the South of Brazil were studied for HTLV-I/II infection. Among 52 individuals, three (5.76%) showed positive anti-HTLV-II antibodies (enzyme-linked immunosorbent assay and Western blot). This preliminary repo…
Mitochondrial Population Genomics Supports a Single Pre-Clovis Origin with a Coastal Route for the Peopling of the Americas
The peopling of America: Craniofacial shape variation on a continental scale and its interpretation from an interdisciplinary view
Twenty‐two years ago, Greenberg, Turner and Zegura ( Curr. Anthropol. 27,477–495, 1986) suggested a multidisciplinary model for the human settlement of the New World. Since their synthesis, several studies based mainly on partial evidence such as skull morphology and molecular genetics have presented competing, apparently mutually exclusive, settlement hypotheses. These contradictory views are represented by the genetic‐based Single Wave or Out o…
Distribution of Y‐chromosome q lineages in native americans
Objectives: This investigation was performed to identify and evaluate the distribution of all 15 Y‐chromosome lineages belonging to the Q clade in a sample of natives from South America. Methods: One hundred and forty‐eight individuals from 20 Native American populations, as well as 24 Asian samples including Eskimos, were tested with 18 biallelic loci that can identify all currently known lineages of the Y‐Chromosome Q clade. Sequencing was perf…
A new subhaplogroup of native American Y-Chromosomes from the Andes
The human Y chromosome contains highly informative markers for making historical inferences about the pre-Columbian peopling of Americas. However, the scarcity of these markers has limited its use in the inference of shared ancestry and past migrations relevant to the origin of the culturally and biologically diverse Native Americans. To identify new single nucleotide polymorphisms (SNPs) and increase the phylogenetic resolution of the major hapl…
The population genetics of quechuas, the largest native south american group: Autosomal sequences, SNPs, and microsatellites evidence high level of diversity
Elucidating the pattern of genetic diversity for non‐European populations is necessary to make the benefits of human genetics research available to individuals from these groups. In the era of large human genomic initiatives, Native American populations have been neglected, in particular, the Quechua, the largest South Amerindian group settled along the Andes. We characterized the genetic diversity of a Quechua population in a global setting, usi…
Ancient remains and the first peopling of the A mericas: Reassessing the Hoyo Negro skull
OBJECTIVE: A noticeably well-preserved ∼12.500 years-old skeleton from the Hoyo Negro cave, Yucatán, México, was recently reported, along with its archaeological, genetic and skeletal characteristics. Based exclusively on an anatomical description of the skull (HN5/48), Chatters and colleagues stated that this specimen can be assigned to a set of ancient remains that differ from modern Native Americans, the so called "Paleoamericans". Here, we ai…
Phylogeographic evidence for two species of muriqui (genus Brachyteles )
The taxonomy of muriquis, the largest extant primates in the New World, is controversial. While some specialists argue for a monotypic genus ( Brachyteles arachnoides ), others favor a two‐species classification, splitting northern muriquis ( Brachyteles hypoxanthus ) from southern muriquis ( B. arachnoides ). This uncertainty affects how we study the differences between these highly endangered and charismatic primates, as well as the design of m…
Hybridization Between Neotropical Primates with Contrasting Sexual Dichromatism
Biology (18 works) · Evolutionary biology (16 works) · Forensic and Genetic Research (14 works) · Demography (12 works) · Gene (12 works) · Population (12 works) · Genetics (11 works) · Genetics (9 works) · Geography (9 works) · Genetic diversity and population structure (7 works)