Deborah A Lawlor
Dados Biográficos
| ID | 1741053 |
|---|---|
| NOME | Deborah A Lawlor |
| PRENOMES | Deborah A |
| SOBRENOME | Lawlor |
| ASSINATURA | LAWLOR D A |
| AFILIAÇÕES | University of Bristol |
| ORCID | 0000-0002-6793-2262 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 115 |
| TOTAL DE CITAÇÕES | 552 |
| TOTAL COMO AUTOR | 115 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1999 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 12 |
Effect of comprehensive tobacco control policies on maternal and child outcomes
Comprehensive tobacco control measures were associated with reduction in maternal smoking during pregnancy, pre-eclampsia and SGA, underscoring their potential to improve perinatal outcomes and supporting the global implementation of WHO-recommended tobacco-control strategies
Socioeconomic position during pregnancy and pre-school exposome in children from eight European birth cohort studies
Distribution of environmental hazards and vulnerability to their effects vary across socioeconomic groups. Our objective was to analyse the relationship between child socioeconomic position (SEP) at birth and the external exposome at pre-school age (0-4 years). This study included more than 60,000 children from eight cohorts in eleven European cities (Oslo, Copenhagen, Bristol, Bradford, Rotterdam, Nancy, Poitiers, Gipuzkoa, Sabadell, Valencia an…
Time-sensitive testing pressures and Covid-19 outcomes
The association between SEP and SARS-CoV-2 testing changed over time, highlighting the potential of time-specific selection pressures to bias analyses of COVID-19. Positive and negative control analyses suggest that changes in the association between SEP and SARS-CoV-2 infection over time likely reflect true increases in socioeconomic inequalities
Mental health before and during the Covid-19 pandemic in two longitudinal UK population cohorts
Background The COVID-19 pandemic and mitigation measures are likely to have a marked effect on mental health. It is important to use longitudinal data to improve inferences. Aims To quantify the prevalence of depression, anxiety and mental well-being before and during the COVID-19 pandemic. Also, to identify groups at risk of depression and/or anxiety during the pandemic. Method Data were from the Avon Longitudinal Study of Parents and Children (…
Age at puberty and accelerometer-measured physical activity
We found a positive association between puberty timing and PA in females which weakened at older ages and limited evidence of an association at any age in males
A Multilevel Analysis of Neighbourhood, School, Friend and Individual-Level Variation in Primary School Children’s Physical Activity
Physical activity is influenced by individual, inter-personal and environmental factors. In this paper, we explore the variability in children's moderate-to-vigorous physical activity (MVPA) at different individual, parent, friend, school and neighbourhood levels. Valid accelerometer data were collected for 1077 children aged 9, and 1129 at age 11, and the average minutes of MVPA were derived for weekdays and weekends. We used a multiple-membersh…
Growing up in Bradford
Our multi-method approach to recruitment and assessment provides an efficient method of collecting rich data on all family members. Data collected will enhance BiB as a resource for the international research community to study the interplay between ethnicity, socioeconomic circumstances and biology in relation to cardiometabolic health, mental health, education, cognitive and sensorimotor development and wellbeing
Experiencing menopause in the UK
We investigated the experience and perspectives of menopause among 48 UK mothers through qualitative in-depth interviews. Interviews were analyzed thematically then explored using social science theories. Three interdependent narratives emerged: menopause as a normal, biological process, distinct from self and social transitions; menopause as struggle, an "idiom of distress" expressing upset, identity loss, shame, and social upheaval; and menopau…
“In my day…”- Parents’ Views on Children’s Physical Activity and Screen Viewing in Relation to Their Own Childhood
Physical activity and screen viewing are associated with cardio-metabolic risk factors, psychological wellbeing, and academic performance among children. Across the last generation, children's physical activity and screen viewing behaviours have changed, coinciding with changes to the home and neighbourhood environment. This study aimed to qualitatively explore parents' views on their 8−9-year-old child's childhood and how this compares to experi…
Parents’ perspectives of change in child physical activity & screen-viewing between Y1 (5-6) & Y4 (8-9) of primary school
Parents reported that children's physical activity and sedentary screen behaviours change between Year 1 and Year 4 with children obtaining increased licence to influence the type, location and frequency with which they are active or sedentary. These changes and rapid advances in screen-viewing technology are a challenge for parents to negotiate and highlight a need to develop innovative and flexible strategies to help parents adapt to a rapidly …
It's the mother
Research on the developmental origins of health and disease (DOHaD) has traditionally focused on how maternal exposures around the time of pregnancy might influence offspring health and risk of disease. We acknowledge that for some exposures this is likely to be correct, but argue that the focus on maternal pregnancy effects also reflects implicit and deeply-held assumptions that 1) causal early life exposures are primarily transmitted via matern…
Prospective associations of psychosocial adversity in childhood with risk factors for cardiovascular disease in adulthood
We found no evidence that exposure to greater psychosocial adversity, or specific forms of psychosocial adversity during childhood is associated with adult CVD risk factors. Further large population studies are needed to clarify whether parental death is associated with higher systolic and diastolic blood pressure
Born in Bradford’s Better Start
The focus of the BiBBS cohort is on intervention impact rather than observation. As far as we are aware BiBBS is the world's first such experimental birth cohort study. While some risk factors for adverse health and social outcomes are increasingly well described, the solutions to tackling them remain elusive. The novel design of BiBBS can contribute much needed evidence to inform policy makers and practitioners about effective approaches to impr…
Examining a conceptual model of parental nurturance, parenting practices and physical activity among 5-6 year olds
Association of Cardiometabolic Multimorbidity With Mortality
IMPORTANCE The prevalence of cardiometabolic multimorbidity is increasing. OBJECTIVE To estimate reductions in life expectancy associated with cardiometabolic multimorbidity. DESIGN, SETTING, AND PARTICIPANTS Age-and sex-adjusted mortality rates and hazard ratios (HRs) were calculated using individual participant data from the Emerging Risk Factors Collaboration (689 300 participants; 91 cohorts; years of baseline surveys: 1960-2007; latest morta…
The Active for Life Year 5 (Afly5) school-based cluster randomised controlled trial
Current Controlled Trials ISRCTN50133740. Registered 17/03/2011
Lessons learned from the Afly5 RCT process evaluation
ISRCTN50133740
Using latent class analysis to develop a model of the relationship between socioeconomic position and ethnicity
LCA allows different aspects of an individual's SEP to be considered in one multidimensional indicator, which can then be integrated in epidemiological analyses. Ethnicity is strongly associated with these identified subgroups. Findings from this study suggest a careful use of SEP measures in health research, especially when looking at different ethnic groups. Further replication of these findings is needed in other populations
Associations between objectively assessed child and parental physical activity
29% of boys and 47% of girls aged five to six years did not meet PA guidelines indicating that these children would benefit from new approaches that focus on increasing physical activity. There were weak associations between the MVPA of 5-6 year old children and their parents, demonstrating that the time that children are active with their parents is not a major source of physical activity. Clinicians and public health professionals should encour…
Skin pigmentation, sun exposure and vitamin D levels in children of the Avon Longitudinal Study of Parents and Children
In this population taking protective measures against sunburn and skin cancer does not seem to remove the positive effect that having a less pigmented skin has on vitamin D production. Our findings require further replication as skin pigmentation showed only a small effect on circulating 25(OH)D
Socioeconomic differences in childhood length/height trajectories in a middle-income country
Current Controlled Trials: NCT01352247 assigned 9 Sept 2005; ClinicalTrials.gov. Identifier: NCT01561612 received 20 Mar 2012
Cohort Profile
The Avon Longitudinal Study of Parents and Children (ALSPAC) is a transgenerational prospective observational study investigating influences on health and development across the life course. It considers multiple genetic, epigenetic, biological, psychological, social and other environmental exposures in relation to a similarly diverse range of health, social and developmental outcomes. Recruitment sought to enroll pregnant women in the Bristol ar…
Cohort Profile
The Avon Longitudinal Study of Children and Parents (ALSPAC) was established to understand how genetic and environmental characteristics influence health and development in parents and children. All pregnant women resident in a defined area in the South West of England, with an expected date of delivery between 1st April 1991 and 31st December 1992, were eligible and 13761 women (contributing 13867 pregnancies) were recruited. These women have be…
Exercise for depression
BACKGROUND: Depression is a common and important cause of morbidity and mortality worldwide. Depression is commonly treated with antidepressants and/or psychological therapy, but some people may prefer alternative approaches such as exercise. There are a number of theoretical reasons why exercise may improve depression. This is an update of an earlier review first published in 2009. OBJECTIVES: To determine the effectiveness of exercise in the tr…
Trajectories of socioeconomic inequalities in health, behaviours and academic achievement across childhood and adolescence
BACKGROUND: Socioeconomic inequalities are a key policy challenge. Studies to date have not taken a unified approach to assess how socioeconomic inequalities in health, behaviour and educational attainment change as children age. METHODS: We examined maternal education inequalities in multiple offspring health, behavioural and educational outcomes and how these changed across childhood and adolescence in the Avon Longitudinal Study of Parents and…
Indicators of socioeconomic position (part 1)
This glossary presents a comprehensive list of indicators of socioeconomic position used in health research. A description of what they intend to measure is given together with how data are elicited and the advantages and limitation of the indicators. The glossary is divided into two parts for journal publication but the intention is that it should be used as one piece. The second part highlights a life course approach and will be published in th…
Indicators of socioeconomic position (part 2)
This is the second part of a glossary on indicators of socioeconomic position used in health research (the first part was published in the January issue of the journal)
Smoking and Ill Health
The resistance of disadvantaged groups to anti-smoking advice is remarkable. In relation to the study of differing cultures, there is a long-standing academic tradition assuming that behavior that may otherwise be difficult to understand is indeed rational within particular cultural contexts. Persistent smoking among the most deprived members of society may represent a rational response to their life chances informed by a lay epidemiology. Health…
Teenage children of teenage mothers
Accuracy of adults’ recall of childhood social class
Background: Although adult reported childhood socioeconomic position has been related to health outcomes in many studies, little is known about the validity of such distantly recalled information. This study evaluated the validity of adults’ reports of childhood paternal social class. Methods: Data are drawn from the Aberdeen children of the 1950s study, a cohort of 12 150 people born in Aberdeen (Scotland) who took part in a school based survey …
It's the mother
Research on the developmental origins of health and disease (DOHaD) has traditionally focused on how maternal exposures around the time of pregnancy might influence offspring health and risk of disease. We acknowledge that for some exposures this is likely to be correct, but argue that the focus on maternal pregnancy effects also reflects implicit and deeply-held assumptions that 1) causal early life exposures are primarily transmitted via matern…
Geographical variation in cardiovascular disease, risk factors, and their control in older women
Objectives: To measure the geographical variation in prevalence of cardiovascular disease, risk factors, and their control in a nationally representative sample of older British women. Methods: Baseline survey using general practitioner record review, a self completed questionnaire, research nurse interview, and physical examination in a randomly selected sample of women aged 60–79 drawn from 23 towns in England, Scotland, and Wales. Results: Of …
Adverse socioeconomic position across the lifecourse increases coronary heart disease risk cumulatively
Objective: To examine the associations of childhood and adult measurements of socioeconomic position with coronary heart disease (CHD) risk. Methods: Cross sectional and prospective analysis of a cohort of 4286 British women who were aged 60–79 years at baseline. Among these women there were 694 prevalent cases of CHD and 182 new incident cases among 13 217 person years of follow up of women who were free of CHD at baseline. Results: All measurem…
Association Between Childhood Socioeconomic Status and Coronary Heart Disease Risk Among Postmenopausal Women
Objectives. We assessed the association between childhood socioeconomic status (SES) and coronary heart disease among postmenopausal women. Methods. We conducted a cross-sectional analysis of 3444 women aged 60 to 79 years. Results. There was an independent linear association between childhood and adult SES and coronary heart disease. The association between childhood SES and coronary heart disease was attenuated when we adjusted for insulin resi…
Childhood Socioeconomic Position, Educational Attainment, and Adult Cardiovascular Risk Factors
Objectives. We assessed the associations of childhood socioeconomic position with cardiovascular disease risk factors (smoking, binge alcohol drinking, and being overweight) and examined the roles of educational attainment and cognitive functioning in these associations. Methods. Data were derived from a cohort study involving 7184 individuals who were born in Aberdeen, Scotland, between 1950 and 1956; had detailed records on perinatal characteri…
Socioeconomic differences in childhood growth trajectories
BACKGROUND: Socioeconomic differentials in adult height are frequently observed, but the age at which these inequalities emerge and the patterns they follow through childhood are unknown. SUBJECTS AND METHODS: Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC), height trajectories from birth to 10 years (N=12366) were modelled. Individual trajectories were estimated using mixed-effects models. Differences in trajectories…
Socioeconomic Position, Co-Occurrence of Behavior-Related Risk Factors, and Coronary Heart Disease
Objectives. We examined the associations between socioeconomic position, co-occurrence of behavior-related risk factors, and the effect of these factors on the relative and absolute socioeconomic gradients in coronary heart disease. Methods. We obtained the socioeconomic position of 9337 men and 39 255 women who were local government employees aged 17–65 years from employers’ records (the Public Sector Study, Finland). A questionnaire survey in 2…
Life-Course Socioeconomic Position, Area Deprivation, and Coronary Heart Disease
Objectives. We sought to determine whether residential area deprivation, over and above the effect of life-course socioeconomic status or position (SEP), is associated with coronary heart disease. Methods. We conducted a cross-sectional analysis of 4286 women aged 60 to 79 years from 457 British electoral wards. Results. After adjustment for age and 10 indicators of individual life-course SEP, the odds of coronary heart disease was 27% greater am…
Early life predictors of childhood intelligence
Objective: To identify the early life predictors of childhood intelligence. Design: Cohort study of 10 424 children who were born in Aberdeen (Scotland) between 1950 and 1956. Results: Social class of father around the time of birth, gravidity, maternal age, maternal physical condition, whether the child was born outside of marriage, prematurity, intrauterine growth, and childhood height were all independently associated with childhood intelligen…
Is housework good for health? Levels of physical activity and factors associated with activity in elderly women. Results from the British Women's Heart and Health Study
Objective: To determine the prevalence of achieving new recommended levels of physical activity, the types of activity involved, and their determinants among elderly British women. Design: National cross sectional survey. Participants: 2341 women aged 60 to 79 from 15 British towns. Main outcome measures: Prevalence of subjects achieving recommended levels of physical activity. Results: Over two thirds of the participants were active at new recom…
Influence of Life Course Socioeconomic Position on Older Women's Health Behaviors
Objectives. We examined the association between health behaviors and socioeconomic status (SES) in childhood and adult life. Methods. Self-reported diet, smoking, and physical activity were determined among 3523 women aged 60 to 79 years recruited from general practices in 23 British towns from 1999 through 2001. Results. The most affluent women reported eating more fruit, vegetables, chicken, and fish and less red or processed meat than did less…
Family Socioeconomic Position at Birth and Future Cardiovascular Disease Risk
Objectives. We assessed the association of father’s social class, recorded at the time of birth, with coronary heart disease and stroke in a British cohort of 11106 individuals born in the 1950s. Methods. Survival analysis was used to relate social class at birth to the occurrence of either fatal or nonfatal coronary heart disease or stroke. Results. Rates of coronary heart disease and stroke increased across the social class distribution from hi…
Socioeconomic Position and Hormone Replacement Therapy Use
Objectives. We assessed the association between life-course socioeconomic status or position (SEP) and hormone replacement therapy (HRT). Methods. We conducted a cross-sectional analysis of 4286 women aged 60 to 79 years. Results. Women experiencing adverse socioeconomic circumstances across the life course were less likely to have used HRT. The associations of childhood socioeconomic measures with HRT use were independent of adult SEP, behaviora…
Physical activity in older women
OBJECTIVE: To assess the association between residential area-level deprivation, individual life-course socioeconomic position and adult levels of physical activity in older British women. METHODS: A cross-sectional study of 4286 British women aged 60-79 years at baseline, who were randomly selected from general practitioner lists in 23 British towns between April 1999 and March 2001 (the British Women's Heart and Health Study). RESULTS: All thre…
The challenges of evaluating environmental interventions to increase population levels of physical activity
Microglia, the innate immune cells of the brain, are exquisitely sensitive to dynamic changes in the neural environment. Using single cell RNA sequencing of the postnatal somatosensory cortex during topographic remapping, we identified a type I interferon (IFN-I) responsive microglia population that expanded with this developmental stressor. Using the marker gene IFITM3 we found that IFN-I responsive microglia were engulfing whole neurons. Loss o…
Trajectories of socioeconomic inequalities in health, behaviours and academic achievement across childhood and adolescence
BACKGROUND: Socioeconomic inequalities are a key policy challenge. Studies to date have not taken a unified approach to assess how socioeconomic inequalities in health, behaviour and educational attainment change as children age. METHODS: We examined maternal education inequalities in multiple offspring health, behavioural and educational outcomes and how these changed across childhood and adolescence in the Avon Longitudinal Study of Parents and…
Season of birth and childhood intelligence
Background. In this study, 2 main hypotheses have been put forward to explain the variation in childhood intelligence or school performance by season of birth. In the first hypothesis, it is suggested that it is due to school policy concerning school entry, whereas the second suggests that a seasonally patterned exposure such as temperature, maternal nutrition, or infection during critical periods of brain development have a lasting effect on int…
Birth weight is inversely associated with coronary heart disease in post-menopausal women
Objectives: (1) To assess the association between birth weight and coronary heart disease (CHD) risk in a cohort of post-menopausal women, (2) to determine the combined effects of birth weight and adult body mass index on CHD, (3) to assess the role of insulin resistance as a mediating factor in the associations. Design: Cross sectional survey. Setting: 23 British towns. Participants: 1394 women aged 60–79 years. Main outcome measures: coronary h…
Rurality, deprivation, and excess winter mortality
The reasons for the higher levels of excess winter mortality in Britain, compared with countries with colder winters, are unclear. Ecological studies suggest that both increased outdoor and indoor cold exposure relating to poor housing energy efficiency and lack of adequate clothing and physical activity when outdoors are important.1,2 It seems plausible that excess winter mortality would be greater in more deprived areas as deprived populations …
Examining a conceptual model of parental nurturance, parenting practices and physical activity among 5-6 year olds
Deprivation and excess winter mortality
Sex differences in risk factors, treatment and mortality after acute myocardial infarction
BACKGROUND: Coronary heart disease is the major cause of death of postmenopausal women in industrialised countries. Although acute myocardial infarction (AMI) affects men in greater numbers, the short-term outcomes for women are worse. In the longer term, studies suggest that mortality risk for women is lower or similar to that of men. However, length of follow up and adjustment for confounding factors have varied and more importantly, the associ…
Water, tobacco, and global inequalities
These photographs are used to illustrate the public health impact of lack of water and global inequalities. Southern Africa experienced one of the worst droughts in history in the early 1990s. For Mozambique, one of the world's poorest countries and at the time devastated by the effects of a US and South African backed guerrilla war the impact was immense. The first photo shows
Water, tobacco, and global inequalities
Objective: Explore adolescents' response to current and potential tobacco control policy issues. Design: The 13 site Tobacco Control Network (TCN), sponsored by the Centers for Disease Control and Prevention, conducted 129 sex and ethnic homogeneous focus groups. Participants: 785 white, African American, Asian American/Pacific Islander, American Indian, and Hispanic adolescents who were primarily smokers from rural, urban, and suburban locations…
Rurality, deprivation, and excess winter mortality
The reasons for the higher levels of excess winter mortality in Britain, compared with countries with colder winters, are unclear. Ecological studies suggest that both increased outdoor and indoor cold exposure relating to poor housing energy efficiency and lack of adequate clothing and physical activity when outdoors are important.1,2 It seems plausible that excess winter mortality would be greater in more deprived areas as deprived populations …
Is housework good for health? Levels of physical activity and factors associated with activity in elderly women. Results from the British Women's Heart and Health Study
Objective: To determine the prevalence of achieving new recommended levels of physical activity, the types of activity involved, and their determinants among elderly British women. Design: National cross sectional survey. Participants: 2341 women aged 60 to 79 from 15 British towns. Main outcome measures: Prevalence of subjects achieving recommended levels of physical activity. Results: Over two thirds of the participants were active at new recom…
Geographical variation in cardiovascular disease, risk factors, and their control in older women
Objectives: To measure the geographical variation in prevalence of cardiovascular disease, risk factors, and their control in a nationally representative sample of older British women. Methods: Baseline survey using general practitioner record review, a self completed questionnaire, research nurse interview, and physical examination in a randomly selected sample of women aged 60–79 drawn from 23 towns in England, Scotland, and Wales. Results: Of …
Performance of the WHO Rose angina questionnaire in post-menopausal women
Objective: To assess the performance of a shortened version of the Rose angina questionnaire focusing on exertional chest pain. Methods: Cross sectional analysis of 3987 women aged 60 to 79 years from 23 British towns. The performances of definite Rose angina (using data from the full Rose angina questionnaire) and exertional chest pain (using data from a subset of three questions from the Rose angina questionnaire) were assessed against a medica…
Association between offspring birth weight and atherosclerosis in middle aged men and women
L ow birth weight is associated with cardiovascular disease in adulthood, but the mechanisms underlying these associations remain unclear.1 One possibility is that poor intra-uterine nutrition “programmes” adult disease.1 An alternative hypothesis is that specific polymorphisms with pleiotrophic effects result in both small birth size and cardiovascular disease risk.2 Epidemiological evidence for a genetic role in the association comes from the r…
The challenges of evaluating environmental interventions to increase population levels of physical activity
Microglia, the innate immune cells of the brain, are exquisitely sensitive to dynamic changes in the neural environment. Using single cell RNA sequencing of the postnatal somatosensory cortex during topographic remapping, we identified a type I interferon (IFN-I) responsive microglia population that expanded with this developmental stressor. Using the marker gene IFITM3 we found that IFN-I responsive microglia were engulfing whole neurons. Loss o…
Lawlor Et Al. Respond
Bassett points out that our analysis ignores targeted marketing by tobacco companies and that to see smoking prevalence as an outcome only of personal choice is an incomplete view. We, along with Bassett and others, deplore the tactics of the tobacco industry.1–3 We did not claim in our article that the smoking prevalence observed in a population was the result only of personal choice. We pointed out that socioeconomic inequalities acting through…
Smoking and Ill Health
The resistance of disadvantaged groups to anti-smoking advice is remarkable. In relation to the study of differing cultures, there is a long-standing academic tradition assuming that behavior that may otherwise be difficult to understand is indeed rational within particular cultural contexts. Persistent smoking among the most deprived members of society may represent a rational response to their life chances informed by a lay epidemiology. Health…
Birth weight is inversely associated with coronary heart disease in post-menopausal women
Objectives: (1) To assess the association between birth weight and coronary heart disease (CHD) risk in a cohort of post-menopausal women, (2) to determine the combined effects of birth weight and adult body mass index on CHD, (3) to assess the role of insulin resistance as a mediating factor in the associations. Design: Cross sectional survey. Setting: 23 British towns. Participants: 1394 women aged 60–79 years. Main outcome measures: coronary h…
Sex differences in body fat distribution and carotid intima media thickness
Objective: To determine the role of central adiposity in explaining sex differences in carotid intima media thickness (IMT). Design: Cross sectional survey. Setting: Two British towns. Participants: 800 men and women aged 56–75 years. Main outcome measures: Carotid IMT. Results: There was a continuous linear association between waist-hip ratio and IMT in both men and women. The magnitude of the association between waist to hip ratio and IMT was i…
Association Between Childhood Socioeconomic Status and Coronary Heart Disease Risk Among Postmenopausal Women
Objectives. We assessed the association between childhood socioeconomic status (SES) and coronary heart disease among postmenopausal women. Methods. We conducted a cross-sectional analysis of 3444 women aged 60 to 79 years. Results. There was an independent linear association between childhood and adult SES and coronary heart disease. The association between childhood SES and coronary heart disease was attenuated when we adjusted for insulin resi…
Socioeconomic Position and Hormone Replacement Therapy Use
Objectives. We assessed the association between life-course socioeconomic status or position (SEP) and hormone replacement therapy (HRT). Methods. We conducted a cross-sectional analysis of 4286 women aged 60 to 79 years. Results. Women experiencing adverse socioeconomic circumstances across the life course were less likely to have used HRT. The associations of childhood socioeconomic measures with HRT use were independent of adult SEP, behaviora…
Socioeconomic Position, Cognitive Function, and Clustering of Cardiovascular Risk Factors in Adolescence
OBJECTIVES: The objectives of this study were to examine the extent of clustering of smoking, high levels of television watching, overweight, and high blood pressure among adolescents and whether this clustering varies by socioeconomic position and cognitive function. METHODS: This study was a cross-sectional analysis of 3613 (1742 females) participants of an Australian birth cohort who were examined at age 14. RESULTS: Three hundred fifty-three …
Asthma and Internalizing Behavior Problems in Adolescence
OBJECTIVE: Clinical studies of asthmatic children have found an association between lung disease and internalizing behavior problems. The causal direction of this association is, however, unclear. This article examines the nature of the relationship between behavior and asthma problems in childhood and adolescence. METHODS: Data were analyzed on 5135 children from the Mater University Study of Pregnancy and its outcomes (MUSP), a large birth coho…
Association between childhood and adulthood socioeconomic position and pregnancy induced hypertension
Background: Pregnancy induced hypertension may indicate a tendency towards endothelial and metabolic abnormalities leading to future cardiovascular disease. Childhood socioeconomic adversity is associated with increased cardiovascular disease risk but the association with pregnancy induced hypertension is unknown. Aim: To examine the association of childhood and adulthood socioeconomic position with pregnancy induced hypertension. Design: Histori…
Early life predictors of childhood intelligence
Objective: To identify the early life predictors of childhood intelligence. Design: Cohort study of 10 424 children who were born in Aberdeen (Scotland) between 1950 and 1956. Results: Social class of father around the time of birth, gravidity, maternal age, maternal physical condition, whether the child was born outside of marriage, prematurity, intrauterine growth, and childhood height were all independently associated with childhood intelligen…
Accuracy of adults’ recall of childhood social class
Background: Although adult reported childhood socioeconomic position has been related to health outcomes in many studies, little is known about the validity of such distantly recalled information. This study evaluated the validity of adults’ reports of childhood paternal social class. Methods: Data are drawn from the Aberdeen children of the 1950s study, a cohort of 12 150 people born in Aberdeen (Scotland) who took part in a school based survey …
Intrauterine growth and intelligence within sibling pairs
Objective: To examine the association between intrauterine growth and intelligence. Design: Population based birth cohort study of sibling pairs born within a maximum of three years of each other. Setting: Mater-University women and children’s hospital, Brisbane, Australia. Participants: 235 (470 children) sibling pairs. Results: Among one randomly selected sibling from each pair verbal comprehension at age 5, general intelligence at age 14, and …
Adverse socioeconomic position across the lifecourse increases coronary heart disease risk cumulatively
Objective: To examine the associations of childhood and adult measurements of socioeconomic position with coronary heart disease (CHD) risk. Methods: Cross sectional and prospective analysis of a cohort of 4286 British women who were aged 60–79 years at baseline. Among these women there were 694 prevalent cases of CHD and 182 new incident cases among 13 217 person years of follow up of women who were free of CHD at baseline. Results: All measurem…
Life-Course Socioeconomic Position, Area Deprivation, and Coronary Heart Disease
Objectives. We sought to determine whether residential area deprivation, over and above the effect of life-course socioeconomic status or position (SEP), is associated with coronary heart disease. Methods. We conducted a cross-sectional analysis of 4286 women aged 60 to 79 years from 457 British electoral wards. Results. After adjustment for age and 10 indicators of individual life-course SEP, the odds of coronary heart disease was 27% greater am…
Childhood Socioeconomic Position, Educational Attainment, and Adult Cardiovascular Risk Factors
Objectives. We assessed the associations of childhood socioeconomic position with cardiovascular disease risk factors (smoking, binge alcohol drinking, and being overweight) and examined the roles of educational attainment and cognitive functioning in these associations. Methods. Data were derived from a cohort study involving 7184 individuals who were born in Aberdeen, Scotland, between 1950 and 1956; had detailed records on perinatal characteri…
Medicine (110 obras) · Demography (72 obras) · Population (58 obras) · Environmental health (56 obras) · Internal Medicine (56 obras) · Internal Medicine (50 obras) · Cohort (40 obras) · Cohort study (39 obras) · Gerontology (37 obras) · Socioeconomic status (37 obras)