Hong‐wen Deng
Dados Biográficos
| ID | 4885436 |
|---|---|
| NOME | Hong‐wen Deng |
| PRENOMES | Hong‐wen |
| SOBRENOME | Deng |
| ASSINATURA | DENG H W |
| AFILIAÇÕES | Tulane University |
| ORCID | 0000-0002-0387-8818 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 13 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 13 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2003 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2022 |
| ÍNDICE H | 0 |
Global Research Trends of Artificial Intelligence on Histopathological Images
Cancer has become a major threat to global health care. With the development of computer science, artificial intelligence (AI) has been widely applied in histopathological images (HI) analysis. This study analyzed the publications of AI in HI from 2001 to 2021 by bibliometrics, exploring the research status and the potential popular directions in the future. A total of 2844 publications from the Web of Science Core Collection were included in the…
Associations of physical activity with sarcopenia and sarcopenic obesity in middle-aged and older adults
The associations of exercise frequency with obesity and sarcopenia vary considerably across gender and age groups. Exercise programs need to be individualized to optimize health benefits. Future research exploring physical activity strategies to balance weight reduction and lean mass maintaining is warranted in middle-aged and especially older adults
Malnutrition and its associated factors among elderly Chinese with physical functional dependency
Objective: To assess the prevalence and to identify the associated factors of malnutrition among elderly Chinese with physical functional dependency. Design: Face-to-face interviews using standardised questionnaires were conducted to collect demographic information, health-related issues and psychosocial status. Physical function was measured by the Barthel Index (BI), and nutrition status was assessed by the Mini Nutritional Assessment–Short For…
Differences of height and body mass index of youths in urban vs rural areas in Hunan province of China
There are significant differences in height and BMI between youths raised in urban vs rural areas, and positive growth trends of height and BMI over time (1990s vs 2000s) in youths in Hunan Province of China
Differences of height and body mass index of youths in urban vs rural areas in Hunan province of China
Anthropometric indices as the predictors of trunk obesity in Chinese young adults
Both BMI and WC are more effective predictors of trunk obesity than WHR and C index in Chinese young adults
Variations in Rank gene are associated with adult height in Caucasians
Height is a complex trait significantly influenced by genetic factors, with heritability ranging from 48% to 98%. Previous studies have yielded a number of important genomic regions that may account for the variation of height in human populations. However, more ‘height’ genes still wait for identification. Recent studies have revealed that tumor necrosis factor receptor superfamily member 11a (RANK) is a vital factor for chondroclastic/osteoclas…
The contributions of lean tissue mass and fat mass to bone geometric adaptation at the femoral neck in Chinese overweight adults
Bone geometry may adapt primarily to mechanical load as represented by TBLM, but TBFM seemed to have no independent effect on bone geometry in Chinese overweight subjects
Genetic Determination of Osteoporosis
Osteoporosis is a common disease with strong genetic control. We performed an autosomal linkage scan in a large pedigree-based sample of 4,498 subjects for a composite osteoporosis phenotype that combines osteoporotic fracture (OF) and low bone mineral density (BMD). All of the subjects were U.S. Caucasians recruited in the Omaha area of Nebraska. Sex-specific linkage analyses and autosomal imprinting analyses were also conducted. For conventiona…
Genetic and Environmental Correlations Between Bone Mineral Density and Bone Size in Caucasians
To explore the magnitude of common genetic and environmental effects shared by bone mineral density (BMD) and bone size (BS) in a large sample of 4,489 subjects (2,667 females and 1,822 males) from 582 Caucasian pedigrees, we performed a bivariate variance decomposition analysis to evaluate genetic correlation (rhoG), environmental correlation (rhoE), and phenotypic correlation (rhoP) between BMD and BS at the spine and hip, as well as their "syn…
The genetic, environmental and phenotypic correlations of bone phenotypes at the spine and hip in Chinese
The obtained results suggested that bone size may be used as another surrogate phenotype independently of BMD for eventual elucidation of the pathogenesis of osteoporosis because of the limited correlations between BMD and bone size
Race and sex differences and contribution of height
Osteoporosis is characterized by a loss of bone strength, of which bone size (BS) is an important determinant. However, studies on the factors determining BS are relatively few. The present study evaluated the independent effects of height, age, weight, sex, and race on areal BS at the hip and spine, measured by dual-energy X-ray absorptiometry, while focusing on the differential contributions of height to BS across sex, race, and skeletal site. …
Evidence for a major gene underlying bone size variation in the Chinese
Osteoporosis is a major public health problem defined as a loss of bone strength, of which bone size is an important determinant. In the present study, familial correlation and segregation analyses for the spine and hip bone sizes were performed for the first time in a Chinese sample composed of 393 nuclear families with a total of 1,193 individuals. The results indicate a major gene of codominant inheritance for spine bone size; however, there i…
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Evidence for a major gene underlying bone size variation in the Chinese
Osteoporosis is a major public health problem defined as a loss of bone strength, of which bone size is an important determinant. In the present study, familial correlation and segregation analyses for the spine and hip bone sizes were performed for the first time in a Chinese sample composed of 393 nuclear families with a total of 1,193 individuals. The results indicate a major gene of codominant inheritance for spine bone size; however, there i…
Race and sex differences and contribution of height
Osteoporosis is characterized by a loss of bone strength, of which bone size (BS) is an important determinant. However, studies on the factors determining BS are relatively few. The present study evaluated the independent effects of height, age, weight, sex, and race on areal BS at the hip and spine, measured by dual-energy X-ray absorptiometry, while focusing on the differential contributions of height to BS across sex, race, and skeletal site. …
The genetic, environmental and phenotypic correlations of bone phenotypes at the spine and hip in Chinese
The obtained results suggested that bone size may be used as another surrogate phenotype independently of BMD for eventual elucidation of the pathogenesis of osteoporosis because of the limited correlations between BMD and bone size
Variations in Rank gene are associated with adult height in Caucasians
Height is a complex trait significantly influenced by genetic factors, with heritability ranging from 48% to 98%. Previous studies have yielded a number of important genomic regions that may account for the variation of height in human populations. However, more ‘height’ genes still wait for identification. Recent studies have revealed that tumor necrosis factor receptor superfamily member 11a (RANK) is a vital factor for chondroclastic/osteoclas…
The contributions of lean tissue mass and fat mass to bone geometric adaptation at the femoral neck in Chinese overweight adults
Bone geometry may adapt primarily to mechanical load as represented by TBLM, but TBFM seemed to have no independent effect on bone geometry in Chinese overweight subjects
Genetic Determination of Osteoporosis
Osteoporosis is a common disease with strong genetic control. We performed an autosomal linkage scan in a large pedigree-based sample of 4,498 subjects for a composite osteoporosis phenotype that combines osteoporotic fracture (OF) and low bone mineral density (BMD). All of the subjects were U.S. Caucasians recruited in the Omaha area of Nebraska. Sex-specific linkage analyses and autosomal imprinting analyses were also conducted. For conventiona…
Genetic and Environmental Correlations Between Bone Mineral Density and Bone Size in Caucasians
To explore the magnitude of common genetic and environmental effects shared by bone mineral density (BMD) and bone size (BS) in a large sample of 4,489 subjects (2,667 females and 1,822 males) from 582 Caucasian pedigrees, we performed a bivariate variance decomposition analysis to evaluate genetic correlation (rhoG), environmental correlation (rhoE), and phenotypic correlation (rhoP) between BMD and BS at the spine and hip, as well as their "syn…
Anthropometric indices as the predictors of trunk obesity in Chinese young adults
Both BMI and WC are more effective predictors of trunk obesity than WHR and C index in Chinese young adults
Differences of height and body mass index of youths in urban vs rural areas in Hunan province of China
There are significant differences in height and BMI between youths raised in urban vs rural areas, and positive growth trends of height and BMI over time (1990s vs 2000s) in youths in Hunan Province of China
Differences of height and body mass index of youths in urban vs rural areas in Hunan province of China
Malnutrition and its associated factors among elderly Chinese with physical functional dependency
Objective: To assess the prevalence and to identify the associated factors of malnutrition among elderly Chinese with physical functional dependency. Design: Face-to-face interviews using standardised questionnaires were conducted to collect demographic information, health-related issues and psychosocial status. Physical function was measured by the Barthel Index (BI), and nutrition status was assessed by the Mini Nutritional Assessment–Short For…
Global Research Trends of Artificial Intelligence on Histopathological Images
Cancer has become a major threat to global health care. With the development of computer science, artificial intelligence (AI) has been widely applied in histopathological images (HI) analysis. This study analyzed the publications of AI in HI from 2001 to 2021 by bibliometrics, exploring the research status and the potential popular directions in the future. A total of 2844 publications from the Web of Science Core Collection were included in the…
Associations of physical activity with sarcopenia and sarcopenic obesity in middle-aged and older adults
The associations of exercise frequency with obesity and sarcopenia vary considerably across gender and age groups. Exercise programs need to be individualized to optimize health benefits. Future research exploring physical activity strategies to balance weight reduction and lean mass maintaining is warranted in middle-aged and especially older adults
Medicine (11 obras) · Biology (7 obras) · Body mass index (6 obras) · Internal Medicine (6 obras) · Bone health and osteoporosis research (5 obras) · Bone Metabolism and Diseases (5 obras) · Demography (5 obras) · Genetics (5 obras) · Osteoporosis (5 obras) · Body weight (4 obras)