Wilfried Dimpfel
Dados Biográficos
| ID | 7270141 |
|---|---|
| NOME | Wilfried Dimpfel |
| PRENOMES | Wilfried |
| SOBRENOME | Dimpfel |
| ASSINATURA | DIMPFEL W |
| AFILIAÇÕES | Justus-Liebig-Universität Gießen |
| ORCID | 0000-0002-9930-6733 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 3 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 3 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2013 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2018 |
| ÍNDICE H | 0 |
Effect of Zembrin ® and four of its alkaloid constituents on electric excitability of the rat hippocampus
We have discovered a new structure activity relationship for Sceletium alkaloids. Since attenuation of AMPA mediated transmission has been related to successful adjunctive treatment of epileptic patients), Mesembrenol and Mesembranol may serve as new chemical leads for the development of new drugs for the treatment of epilepsy
Electropharmacogram of Sceletium tortuosum extract based on spectral local field power in conscious freely moving rats
The combined results from the electropharmacograms and comparative discriminatory analyses suggest that Zembrin® has dose dependent activity, with potential applications as a cognitive function enhancer, as an antidepressant, and as an analgesic
Pharmacological classification of herbal extracts by means of comparison to spectral EEG signatures induced by synthetic drugs in the freely moving rat
Herbal extracts targeting at the brain remain a continuous challenge to pharmacology. Usually, a number of different animal tests have to be performed in order to find a potential clinical use. Due to manifold possibly active ingredients biochemical approaches are difficult. A more holistic approach using a neurophysiological technique has been developed earlier in order to characterise synthetic drugs. Stereotactic implantation of four semi-micr…
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Pharmacological classification of herbal extracts by means of comparison to spectral EEG signatures induced by synthetic drugs in the freely moving rat
Herbal extracts targeting at the brain remain a continuous challenge to pharmacology. Usually, a number of different animal tests have to be performed in order to find a potential clinical use. Due to manifold possibly active ingredients biochemical approaches are difficult. A more holistic approach using a neurophysiological technique has been developed earlier in order to characterise synthetic drugs. Stereotactic implantation of four semi-micr…
Electropharmacogram of Sceletium tortuosum extract based on spectral local field power in conscious freely moving rats
The combined results from the electropharmacograms and comparative discriminatory analyses suggest that Zembrin® has dose dependent activity, with potential applications as a cognitive function enhancer, as an antidepressant, and as an analgesic
Effect of Zembrin ® and four of its alkaloid constituents on electric excitability of the rat hippocampus
We have discovered a new structure activity relationship for Sceletium alkaloids. Since attenuation of AMPA mediated transmission has been related to successful adjunctive treatment of epileptic patients), Mesembrenol and Mesembranol may serve as new chemical leads for the development of new drugs for the treatment of epilepsy
Medicine (3 obras) · Pharmacology (3 obras) · Chemical synthesis and alkaloids (2 obras) · Chemistry (2 obras) · Cholinesterase and Neurodegenerative Diseases (2 obras) · Psychiatry (2 obras) · Traditional medicine (2 obras) · Alkaloid (1 obras) · Alkaloids: synthesis and pharmacology (1 obras) · AMPA receptor (1 obras)