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Electropharmacogram of Sceletium tortuosum extract based on spectral local field power in conscious freely moving rats

Dados Bibliográficos

ID14733296
AutoresWilfried Dimpfel (0000-0002-9930-6733, Justus-Liebig-Universität Gießen, autor correspondente), Leonie Schombert, Nigel Gericke (0000-0003-4212-1487)
Ano2016
Volume177
Páginas140-147
Data de publicação2016-01-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoJournal of Ethnopharmacology (JOURNAL)
Identificadores do periódicoISSN: 0378-8741 • E-ISSN: 1872-7573
EditoraElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2015.11.036
PMID26608705
OpenAlexW2185746316
IdiomaEN
Citações recebidas8
Referências citadas14

The combined results from the electropharmacograms and comparative discriminatory analyses suggest that Zembrin® has dose dependent activity, with potential applications as a cognitive function enhancer, as an antidepressant, and as an analgesic

Traditional medicine · Chemical synthesis and alkaloids · Cholinesterase and Neurodegenerative Diseases · Medicine · Psychedelics and Drug Studies · Pharmacology

  • Ameliorative effects of alkaloid extract from Mitragyna speciosa (Korth.) Havil. Leaves on methamphetamine conditioned place preference in mice

    Open Access•Jakkrit Nukitram, Dania Cheaha et al.•Journal of Ethnopharmacology•2022

  • Sceletium tortuosum-derived mesembrine significantly contributes to the anxiolytic effect of Zembrin®, but its anti-depressant effect may require synergy of multiple plant constituents

    Open Access•Johané Gericke, Brian H Harvey et al.•Journal of Ethnopharmacology•2024

  • Mesembrine alkaloids

    Open Access•John L Krstenansky•Journal of Ethnopharmacology•2017

  • Sceletium tortuosum

    Open Access•T L Olatunji, Frances Siebert et al.•Journal of Ethnopharmacology•2021

  • Sceletium tortuosum

    Open Access•T L Olatunji, Frances Siebert et al.•Journal of Ethnopharmacology•2022

  • Differential impact of extracts from distinct Sceletium tortuosum chemotypes on central neurotransmitter concentrations in C57BL/6 mice

    Open Access•Catherine H Kaschula, Anna-Mart Engelbrecht et al.•Journal of Ethnopharmacology•2025

  • Pharmacological and toxicological effects of Ruta chalepensis L. on experimentally induced seizures and electroencephalographic spectral power in mice

    Open Access•María Eva González-Trujano, E Urbina-Trejo et al.•Journal of Ethnopharmacology•2021

  • Effect of Zembrin ® and four of its alkaloid constituents on electric excitability of the rat hippocampus

    Open Access•Wilfried Dimpfel, Richard Franklin et al.•Journal of Ethnopharmacology•2018

  • Dose translation from animal to human studies revisited

    Open Access•Shannon Reagan‐Shaw, Minakshi Nihal et al.•The FASEB Journal•2008

  • Sceletium—A review update

    Open Access•Niklas Gericke, Nigel Gericke et al.•Journal of Ethnopharmacology•2008

  • Pharmacological actions of the South African medicinal and functional food plant Sceletium tortuosum and its principal alkaloids

    Open Access•Alan L Harvey, Louise Young et al.•Journal of Ethnopharmacology•2011

  • Pharmacological classification of herbal extracts by means of comparison to spectral EEG signatures induced by synthetic drugs in the freely moving rat

    Open Access•Wilfried Dimpfel•Journal of Ethnopharmacology•2013

Obras citantes distintas8
Citações por ano0,89
Intervalo de citações2017 - 2025 (9)
Velocidade de citaçãorecent
Altamente citadoNão
Tipos de citaçãoNeutras: 8
Ethnos_APP • Projeto Open Source • Licença MIT • Frontend v2.0.0 • Privacidade e Cookies • Documentação da API: api.ethnos.app/docs • Código da API: GitHub • DOI: 10.5281/zenodo.17049435 • Código do Frontend: GitHub • DOI: 10.5281/zenodo.17050053 • cruz.rio.br • Expectantes Misericordiae