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Duhuo Jisheng decoction alleviates intervertebral disc degeneration by inhibiting nucleus pulposus cell pyroptosis via gallic acid-mediated downregulation of HIF-1α

Dados Bibliográficos

ID14739720
AutoresJunjie Cheng (0009-0000-6455-975X, Zhujiang Hospital), Jianjun Li (0000-0003-2872-9648, Zhujiang Hospital), Cheng Yu (0000-0002-3535-0567, Third Affiliated Hospital of Southern Medical University), Wenhao Kuang (Zhujiang Hospital), Runjun Luo (Dongguan People’s Hospital), Rongze Luo (0000-0002-8131-8277, Dongguan People’s Hospital), Zhihui Zhou (0000-0001-7254-8786, Dongguan People’s Hospital), Jianfeng Zhang (0000-0003-2596-5143, Dongguan People’s Hospital), Yang Duan (0000-0002-6084-1026, Zhujiang Hospital, autor correspondente)
Ano2026
Volume358
Páginas120957
Data de publicação2026-03-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoJournal of Ethnopharmacology (JOURNAL)
Identificadores do periódicoISSN: 0378-8741 • E-ISSN: 1872-7573
EditoraElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2025.120957
PMID41317810
OpenAlexW4416757935
IdiomaEN
Referências citadas41

Apoptosis · Cell · Downregulation and upregulation · Gallic acid · Oxidative stress · Paeoniflorin · Programmed cell death · Pyroptosis · Gout, Hyperuricemia, Uric Acid · Spine and Intervertebral Disc Pathology · Spondyloarthritis Studies and Treatments

  • ClusterProfiler

    Open Access•Guangchuang Yu, Li-Gen Wang et al.•OMICS: A Journal of Integrative…•2012

  • Intervertebral disc degeneration—Current therapeutic options and challenges

    Open Access•Ankita Samanta, Thomas Lufkin et al.•Frontiers in Public Health•2023

  • Duhuo jisheng decoction suppresses matrix degradation and apoptosis in human nucleus pulposus cells and ameliorates disc degeneration in a rat model

    Open Access•Wei Liu, Shuwen Jin et al.•Journal of Ethnopharmacology•2020

  • The effects of Jiawei Duhuo Jisheng mixture on Wnt/β-catenin signaling pathway in the synovium inflamed by knee osteoarthritis

    Open Access•Qiyun Shi, Lu Huang et al.•Journal of Ethnopharmacology•2022

Velocidade de citaçãohistorical
Altamente citadoNão
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