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Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model

Dados Bibliográficos

ID14740437
AutoresLei Yao (0000-0001-7917-2582, Chinese PLA General Hospital), Rui Jing (0000-0002-8924-1665, Chinese PLA General Hospital), Chaochen Wang, Chao-chen Wang (0000-0002-9639-095X, Chinese PLA General Hospital), Yuanbo Wang (0009-0003-4153-4914, Chinese PLA General Hospital), Xia Li (0000-0003-3050-8529, Chinese PLA General Hospital), Xiao Wu (0000-0003-0013-8520, Chinese PLA General Hospital), Yanbo Wang (0000-0002-1566-2125, Chinese PLA General Hospital), Lijun Liu (0000-0002-8628-255X, Chinese PLA General Hospital), Li-Hua Mu (0000-0001-9753-3775, Chinese PLA General Hospital), LiHua Mu, Ping Liu (0000-0002-8713-1999, Chinese PLA General Hospital), Yuan Hu (0000-0002-8951-5881, Chinese PLA General Hospital, autor correspondente)
Ano2025
Volume351
Páginas120011
Data de publicação2025-07-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoJournal of Ethnopharmacology (JOURNAL)
Identificadores do periódicoISSN: 0378-8741 • E-ISSN: 1872-7573
EditoraElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2025.120011
PMID40446976
OpenAlexW4410818612
IdiomaEN
Citações recebidas2
Referências citadas49

Amino acid · Biology · Fluoxetine · Homeostasis · Kynurenine · Receptor · Rodent · Rodent model · Serotonin · Tryptophan · Chemistry · Medicine · Mental Health Research Topics · Stress Responses and Cortisol · Tryptophan and brain disorders · Biochemistry · Ecology · Endocrinology · Internal Medicine · Pharmacology

  • The effects of Kai-Xin-San in alleviating chronic social defeat stress-induced depression-like behaviors are associated with CD4+ T cells

    Open Access•Yanbo Wang, Lijun Liu et al.•Journal of Ethnopharmacology•2026

  • Kai-Xin-San, an ancient herbal mixture for anti-depression, mitigates the fluoxetine-induced gut dysbiosis and intestinal damage in chronic unpredictable mild stressed mice

    Open Access•Jiahui Wu, Xin Li et al.•Journal of Ethnopharmacology•2026

  • Changes in the global burden of depression from 1990 to 2017

    Open Access•Qingqing Liu, Hairong He et al.•Journal of Psychiatric Research•2020

  • Depression

    Open Access•Roger D Porsolt, Manuel Pichon et al.•Nature•1977

  • A representative prescription for emotional disease, Ding-Zhi-Xiao-Wan restores 5-HT system deficit through interfering the synthesis and transshipment in chronic mild stress-induced depressive rats

    Xian-Zhe Dong, Xian‐Zhe Dong et al.•Journal of Ethnopharmacology•2013

  • Kai-Xin-San, a traditional Chinese medicine formula, induces neuronal differentiation of cultured PC12 cells

    Open Access•Yue Zhu, Xiuzhu Duan et al.•Journal of Ethnopharmacology•2016

  • A randomized, placebo-controlled, double-blind study on the effects of SZL on patients with mild to moderate depressive disorder with comparison to fluoxetine

    Open Access•Yuan Hu, Yichen Wang et al.•Journal of Ethnopharmacology•2021

Obras citantes distintas2
Citações por ano2
Intervalo de citações2026 - 2026 (1)
Velocidade de citaçãocurrent
Altamente citadoNão
Tipos de citaçãoNeutras: 2
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