Cardiovascular-Related Outcomes in U.S. Adults Exposed to Lead

Dados Bibliográficos

ID15464178
AutoresEmmanuel Obeng-Gyasi (0000-0003-3195-706X, North Carolina Agricultural and Technical State University, autor correspondente), Rodrigo X Armijos (0000-0002-6748-7832, Indiana University Bloomington), Rodrigo Armijos (Department of Environmental and Occupational Health, Indiana University School of Public Health, Bloomington, IN 47405, USA), M Margaret Weigel (0000-0001-8080-0603, Indiana University Bloomington), M Weigel (Department of Environmental and Occupational Health, Indiana University School of Public Health, Bloomington, IN 47405, USA), Gabriel Filippelli (0000-0003-3434-5982, University of Indianapolis), M Aaron Sayegh (0009-0006-4369-1042, Indiana University Bloomington), M Sayegh (Department of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, IN 47405, USA)
Ano2018
Volume15
Fascículo4
Páginas759-759
Data de publicação2018-04-15
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoInternational Journal of Environmental Research and Public Health (JOURNAL)
Identificadores do periódicoISSN: 1661-7827 • E-ISSN: 1660-4601
EditoraMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph15040759
PMID29662032
OpenAlexW2797696963
IdiomaEN
Citações recebidas12
Referências citadas30

Cardiovascular-related clinical markers were evaluated in this cross-sectional study of United States adults (aged ≥ 20) exposed to lead via the National Health and Nutrition Examination Survey 2007-2008 and the 2009-2010 datasets. In four quartiles of exposure-0-2 μg/dL, 2-5 μg/dL, 5-10 μg/dL, and 10 μg/dL and over, clinical and anthropometric markers were evaluated-to examine how the markers manifested in the quartiles. Associations were determined via linear regression. Finally, clinical makers, and how they manifested between exposed and less-exposed occupations, were explored in addition to how duration of exposure altered these clinical markers. In regression analysis, Diastolic Blood Pressure (DBP) and high-density lipoprotein (HDL) cholesterol, were significantly associated with blood lead level (BLL). In the occupational analysis, Systolic Blood Pressure (SBP), DBP, C-reactive protein (CRP), triglycerides, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, showed differences between populations in the exposed and less-exposed occupations. Regarding Agriculture, Forestry & Fishing, the duration of exposure altered SBP, CRP, and LDL cholesterol. With mining, the duration of exposure altered SBP, DBP, triglycerides, and HDL cholesterol, whereas in construction, the duration in occupation altered SBP, triglycerides, and CRP. In conclusion, lead exposure has a profound effect on the cardiovascular system, with potentially adverse outcomes existing at all exposure levels

Biology · Environmental health · Lead (geology · Lead exposure · Air Quality and Health Impacts · Heavy Metal Exposure and Toxicity · Medicine · Noise Effects and Management · Gerontology · Internal Medicine