The Quantified Behavioral Test—A Confirmatory Test in the Diagnostic Process of Adult ADHD

The differential diagnosis of attention deficit hyperactivity disorder (ADHD) in adulthood is complicated by comorbid disorders, but also by the overlapping of main symptoms such as inattentiveness, impulsivity, and hyperactivity with other disorders. Neuropsychological tests like continuous performance tests (CPT) try to solve this dilemma by objectively measurable parameters. We investigated in a cohort of n=114 patients presenting to an ADHD outpatient clinic how well a commercially available CPT test (QbTest ® ) can differentiate between patients with ADHD (n=94) and patients with a disconfirmed ADHD diagnosis (n=20). Both groups showed numerous comorbidities, predominantly depression (27.2% in the ADHD group vs. 45% in the non-ADHD group) and substance-use disorders (18.1% vs. 10%, respectively). Patients with ADHD showed significant higher activity (2.07 ± 1.23) than patients without ADHD (1.34 ± 1.27, dF=112; p=0.019), whereas for the other core parameters, inattention and impulsivity no differences could be found. Reaction time variability has been discussed as a typical marker for inattention in ADHD. Therefore, we investigated how well ex-Gaussian analysis of response time can differentiate between ADHD and other patients, showing, that it does not help to identify patients with ADHD. Even though patients with ADHD showed significantly higher activity, this parameter differed only poorly between patients (accuracy AUC 65% of an ROC-Curve). We conclude that CPTs do not help to identify patients with ADHD in a specialized outpatient clinic. The usability of this test for differentiating between ADHD and other psychiatric disorders is poor and a sophisticated analysis of reaction time did not decisively increase the test accuracy

Anxiety · Attention deficit · Cambridge Neuropsychological Test Automated Battery · Cognition · Depression (economics · Impulsivity · Mood disorders · Neurocognitive · Neuropsychology · Outpatient clinic · Psychiatry · Working memory · Attention Deficit Hyperactivity Disorder · Clinical Psychology · Functional Brain Connectivity Studies · Medicine · Psychology · Internal Medicine

• Practitioner Review

  Open Access•Alessio Bellato, Charlotte L Hall et al.•Journal of Child Psychology and…•2024

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  Open Access•Mathias Luderer, Johanna Seidt et al.•Frontiers in Psychiatry•2023

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• The World Health Organization adult ADHD self-report scale (ASRS)

  Open Access•R C Kessler, LI Wei-l et al.•Psychological Medicine•2005

  Incluir item

• Genetics of attention deficit hyperactivity disorder

  Open Access•Stephen V Faraone, Henrik Larsson•Molecular Psychiatry•2019

  Incluir item

• Attention-deficit/hyperactivity disorder

  Open Access•Stephen V Faraone, Philip Asherson et al.•Nature Reviews Disease Primers•2015

  Incluir item

• Long-Term Outcomes of Attention-Deficit/Hyperactivity Disorder and Conduct Disorder

  Open Access•Holly E Erskine, Rosana E Norman et al.•Journal of the American Academy…•2016

  Incluir item

• The descriptive epidemiology of DSM-IV Adult ADHD in the World Health Organization World Mental Health Surveys

  Open Access•on behalf of the WHO World Mental Health Survey Collaborators, John Fayyad et…•ADHD Attention Deficit and…•2017

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