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Relationship between spermatogenesis, DNA fragmentation index, and teratozoospermia index

Dados Bibliográficos

ID15794591
AutoresJoice Marlina Budiharto (Airlangga University, autor correspondente), Ria Margiana (0000-0002-6747-0117, University of Indonesia), William William (0000-0002-4474-1703, Atma Jaya Catholic University of Indonesia), Supardi Supardi (0000-0003-3642-1029, Universitas Dr. Soetomo), Pety Narulita (0000-0001-9904-1336, Universitas Dr. Soetomo)
Ano2022
Páginas1827-1837
Data de publicação2022-04-10
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoInternational Journal of Health Sciences (JOURNAL)
Identificadores do periódicoISSN: 2550-696X • E-ISSN: 2550-6978
EditoraUniversidad Tecnica de Manabi (PUBLISHER • EC)
DOI10.53730/ijhs.v6ns3.5808
OpenAlexW4223645084
IdiomaEN
Citações recebidas1
Referências citadas1

Infertility has proven a global medical issue, with 15-20 percent of married worldwide experiencing difficulties in conceiving. One of the causes of male infertility is sperm morphology abnormalities, or teratozoospermia, which is often associated with sperm DNA damage. Teratozoospermia can increase sperm DNA fragmentation through several mechanisms, including abortive apoptosis and induce ROS formation. Unfortunately, many forms of sperm flaws, including genetic defects, could not be validated by routine semen examination. In the Sixth Edition, WHO introduced a more thorough sperm morphology examination, named the teratozoospermia index (TZI), in which every aberrant sperm is examined for up to four defects. Analyzing spermatozoa abnormalities in more detail can provide an overview of the function of the male reproductive organs, particularly the testes and epididymis. However, using this method is not entirely easy due to subnormal variations between cells so that quality control may be needed when using TZI for sperm morphology evaluation

Andrology · Apoptosis · Biology · DNA fragmentation · Infertility · Male infertility · Pregnancy · Semen · Semen Analysis · Sperm · Spermatogenesis · Medicine · Reproductive Biology and Fertility · Reproductive Health and Technologies · Sperm and Testicular Function · Genetics

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Obras citantes distintas1
Citações por ano0,25
Intervalo de citações2022 - 2022 (1)
Velocidade de citaçãohistorical
Altamente citadoNão
Tipos de citaçãoNeutras: 1
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