Neural Correlates of Food Addiction
Dados Bibliográficos
| ID | 23372198 |
|---|---|
| Autores | Ashley N Gearhardt (0000-0003-3843-5731, Yale University, autor correspondente) |
| Ano | 2011 |
| Volume | 68 |
| Fascículo | 8 |
| Páginas | 808 |
| Data de publicação | 2011-08-01 |
| Peer Reviewed | Sim |
| Open Access | Não |
| Tipo | ARTICLE |
| Periódico | Archives of General Psychiatry (JOURNAL) |
| Identificadores do periódico | ISSN: 0003-990X • E-ISSN: 1538-3636 |
| Editora | American Medical Association (AMA) (PUBLISHER) |
| DOI | 10.1001/archgenpsychiatry.2011.32 |
| PMID | 21464344 |
| PMCID | PMC3980851 |
| OpenAlex | W2114683421 |
| Idioma | EN |
| Citações recebidas | 70 |
| Referências citadas | 16 |
CONTEXT: Research has implicated an addictive process in the development and maintenance of obesity. Although parallels in neural functioning between obesity and substance dependence have been found, to our knowledge, no studies have examined the neural correlates of addictive-like eating behavior. OBJECTIVE: To test the hypothesis that elevated "food addiction" scores are associated with similar patterns of neural activation as substance dependence. DESIGN: Between-subjects functional magnetic resonance imaging study. SETTING: A university neuroimaging center. PARTICIPANTS: Forty-eight healthy young women ranging from lean to obese recruited for a healthy weight maintenance trial. MAIN OUTCOME MEASURE: The relation between elevated food addiction scores and blood oxygen level-dependent functional magnetic resonance imaging activation in response to receipt and anticipated receipt of palatable food (chocolate milkshake). RESULTS: Food addiction scores (N = 39) correlated with greater activation in the anterior cingulate cortex, medial orbitofrontal cortex, and amygdala in response to anticipated receipt of food (P < .05, false discovery rate corrected for multiple comparisons in small volumes). Participants with higher (n = 15) vs lower (n = 11) food addiction scores showed greater activation in the dorsolateral prefrontal cortex and the caudate in response to anticipated receipt of food but less activation in the lateral orbitofrontal cortex in response to receipt of food (false discovery rate-corrected P < .05). CONCLUSIONS: Similar patterns of neural activation are implicated in addictive-like eating behavior and substance dependence: elevated activation in reward circuitry in response to food cues and reduced activation of inhibitory regions in response to food intake.
Addiction · Amygdala · Anterior cingulate cortex · Cognition · Craving · Cue reactivity · Dorsolateral prefrontal cortex · Food addiction · Food craving · Functional magnetic resonance imaging · Neural correlates of consciousness · Neuroimaging · Orbitofrontal cortex · Prefrontal cortex · Eating Disorders and Behaviors · Neural and Behavioral Psychology Studies · Neuroscience · Neurotransmitter Receptor Influence on Behavior · Psychology
Behavioral Addictions Questionnaire (BAQ)
Development of the Yale Food Addiction Scale Version 2.0.
Evidence that ‘food addiction’ is a valid phenotype of obesity
Exploration of “Food Addiction” in overweight and obese treatment-seeking adults
Liking, wanting, and the incentive-sensitization theory of addiction
The Cambridge Handbook of Substance and Behavioral Addictions
Emerging Evidence of Addiction in Problematic Eating Behavior
Body Reserves and Food Storage
Which Foods May Be Addictive? The Roles of Processing, Fat Content, and Glycemic Load
The Prevalence of Food Addiction as Assessed by the Yale Food Addiction Scale
The association between cumulative adverse childhood experiences and ultra-processed food addiction is moderated by substance use disorder history among adults seeking outpatient nutrition counseling
Neural underpinnings of threat bias in relation to loss-of-control eating behaviors among adolescent girls with high weight
Emotion Regulation and Mentalization in People at Risk for Food Addiction
Ultra-processed food addiction symptoms profile according to weight status among Brazilian adults
Exploratory study of the prevalence of food addiction and its relationship with executive functioning, depression, and reinforcement sensitivity in a sample of Mexican adults
Case management of ultra-processed food addiction
Changes in binge eating symptoms following an online community-based ultra-processed food addiction intervention
Neuronal inhibitory mechanisms in overweight/obesity and food/eating addiction
The role of maternal empathy and intrusiveness in binge eating disorder among Jewish and Arab women with elevated BMI in Israel
The Question of Sustainability in the Age of Addiction
Suicide et alimentation
Relationship of constipation, body mass index increase and cigarette craving with nutrition in the smoking cessation process
From substances to food
“White Box” Epidemiology and the Social Neuroscience of Health Behaviors
Structural Barriers to Healthy Food and High-Sugar Consumption in Black Young Adult Women
A commentary on the “eating addiction” versus “food addiction” perspectives on addictive-like food consumption
Sensorial pedagogies, hungry fat cells and the limits of nutritional health education
Food addiction and weight in students with high academic performance
The Obesity Epidemic and Food Addiction
A systematic review of the relationship between taste and personality traits
Moving beyond the “eating addiction” versus “food addiction” debate
Food addiction, hormones and blood biomarkers in humans
Neural correlates of inhibitory control in youth with symptoms of food addiction
Food addiction in adults seeking weight loss treatment. Implications for psychosocial health and weight loss
Systematically lower structural brain connectivity in individuals with elevated food addiction symptoms
Food addiction and substance addiction in women
Changes in temporal discounting, hedonic hunger, and food addiction during recovery from substance misuse
Apples or candy? Internal and external influences on children's food choices
Dopamine genetic risk is related to food addiction and body mass through reduced reward-related ventral striatum activity
Childhood trauma and food addiction
Food Addiction in Adolescents
Food addiction symptoms are related to neuroaffective responses to preferred binge food and erotic cues
Wanting and liking
Food addiction as a mediator between depressive symptom severity and body mass index
Food addiction linked to changes in ventral striatum functional connectivity between fasting and satiety
Stress, cues, and eating behavior. Using drug addiction paradigms to understand motivation for food
Independent associations of food addiction and binge eating measures with real-time eating behaviors and contextual factors
Brain structure predicts risk for obesity
Associations of childhood trauma with food addiction and insulin resistance in African-American women with diabetes mellitus
Food addiction’. What happens in childhood
The effects of prefrontal cortex transcranial direct current stimulation (tDCS) on food craving and temporal discounting in women with frequent food cravings
Establishing a food addiction diagnosis using the Yale Food Addiction Scale
Reward sensitivity and food addiction in women
Pattern of access determines influence of junk food diet on cue sensitivity and palatability
Acute responses to opioidergic blockade as a biomarker of hedonic eating among obese women enrolled in a mindfulness-based weight loss intervention trial
Self-perceived food addiction
Harsh, unpredictable childhood environments are associated with inferior frontal gyrus connectivity and binge eating tendencies in late adolescents
Satiety modulates reward processing in food addiction
Symptoms of ‘food addiction’ in binge eating disorder using the Yale Food Addiction Scale version 2.0
The association of addictive-like eating with food intake in children
A sad mood increases attention to unhealthy food images in women with food addiction
Two novel candidate genes identified in adults from the Newfoundland population with addictive tendencies towards food
Food and beverage consumption and food addiction among women in the Nurses' Health Studies
Overeating and food addiction in Major Depressive Disorder
Greater anterior cingulate activation and connectivity in response to visual and auditory high-calorie food cues in binge eating
Greater corticolimbic activation to high-calorie food cues after eating in obese vs. normal-weight adults
The bioSocial Cognitive Theory of eating (bSCT-e)
Exploring food reward and calorie intake in self-perceived food addicts
Individual differences in appeal of energy dense foods predicts lower body mass change during adolescence
A randomized experiment of the effects of food advertisements on food-related emotional expectancies in adults
Relation of reward from food intake and anticipated food intake to obesity
On being led into temptation
Widespread reward-system activation in obese women in response to pictures of high-calorie foods
Self-Control in Decision-Making Involves Modulation of the vmPFC Valuation System
Affective neuroscience of pleasure
Actual Causes of Death in the United States, 2000
Actual Causes of Death in the United States
Brain dopamine and obesity
Epidemiology of alcohol and other drug use among American college students.
Alcohol abuse and dependence among U.S. college students.
The tempted brain eats
Breakdown of dietary restraint following mere exposure to food stimuli
Incentive‐sensitization and addiction
The Effect of Pre-exposure to Food Cues on the Eating Behavior of Restrained and Unrestrained Eaters
Preliminary validation of the Yale Food Addiction Scale
| Obras citantes distintas | 70 |
|---|---|
| Citações por ano | 4,67 |
| Intervalo de citações | 2011 - 2026 (16) |
| Velocidade de citação | current |
| Altamente citado | Não |
| Tipos de citação | Neutras: 65 |