D1S80 Single-Locus Discrimination Among African Populations

Dados Bibliográficos

ID6068352
AutoresRene J Herrera (0000-0002-5119-4381, Florida International University), Leslie R Adrien, Luis M Ruiz, Nahir Y Sanabria, George Duncan, George T Duncan (0000-0002-4931-5316)
Ano2004
Volume76
Fascículo1
Páginas87-108
Data de publicação2004-01-01
Peer ReviewedSim
Open AccessNão
TipoARTICLE
PeriódicoHuman Biology (JOURNAL)
Identificadores do periódicoISSN: 0018-7143 • E-ISSN: 1534-6617
EditoraProject MUSE (PUBLISHER • US)
DOI10.1353/hub.2004.0022
PMID15222682
OpenAlexW2043663804
IdiomaEN
Citações recebidas7
Referências citadas9

The highly polymorphic D1S80 locus has no known genetic function. However, this variable number of tandem repeats (VNTR) locus has been highly valuable in forensic identification. In this study we report the allele and genotype frequencies of five African populations (Benin, Cameroon, Egypt, Kenya, and Rwanda), which can be used as databases to help characterize populations and identify individuals. The allele frequencies were used to infer genetic associations through phylogenetic, principal component, and G test statistical analyses. Compliance with Hardy-Weinberg equilibrium expectations was determined as were F(ST) estimates, theta p values, and power of discrimination assessment for each population. Our analyses of 28 additional populations demonstrate that the D1S80 locus alone can be used to discriminate geographic and ethnic groups. We have generated databases useful for human identification and phylogenetic studies

Allele · Allele frequency · Biology · Evolutionary biology · Gene · Genotype · Locus (genetics) · Phylogenetic tree · Population · Variable number tandem repeat · Demography · Forensic and Genetic Research · Genetic diversity and population structure · Genetics · Identification and Quantification in Food