Peopling of Myanmar as Demonstrated by Genotyping of Urinary JC Virus DNA

Dados Bibliográficos

ID6135589
AutoresLei Saruwatari (Aichi Gakuin University), Huai-Ying Zheng (The University of Tokyo), Tomokazu Takasaka (The University of Tokyo), Chie Sugimoto (0000-0002-0488-2931, The University of Tokyo), Eiichi Sakai (0000-0001-6097-565X, Aichi Gakuin University), Bo Bo (Institute of Dental Medicine), Nwe Nwe Aung (Institute of Dental Medicine), Tadaichi Kitamura (0000-0002-3009-2546, The University of Tokyo), Yoshiaki Yogo (The University of Tokyo), Norikazu Ohno (Aichi Gakuin University)
Ano2002
Volume110
Fascículo3
Páginas235-249
Data de publicação2002-01-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoAnthropological Science (JOURNAL)
Identificadores do periódicoISSN: 0918-7960 • E-ISSN: 1348-8570
EditoraAnthropological Society of Nippon (PUBLISHER • JP)
DOI10.1537/ase.110.235
OpenAlexW1999806028
IdiomaEN
Citações recebidas9
Referências citadas8

The genotyping of urinary JC virus (JCV) DNAs is a novel means of elucidating the origin of ethnic populations. We adopted this method to gain insights into the peopling of Myanmar. JCV genotype profiles at two sites of Myanmar, Yangon facing the Andaman Sea and Peinnebeen located in the central part of Myanmar, were reported previously. In this study, we elucidated JCV genotype profiles at three other sites of Myanmar: Chaungtha Beach facing the Bay of Bengal, Myitkyina located near China and Tiddim located near India. From the JCV genotype profiles at the five sites elucidated here and previously, it is suggested that SC, the southeastern-Asian/southern-Chinese subtype, mainly occurrs throughout Myanmar, and that a few minor subtypes occur at southern and northern sites (Yangon, Chaungtha Beach and Myitkyina). Furthermore, using the whole-genome approach, we evaluated the phylogenetic relationships among various SC isolates detected in Myanmar and other countries. The results of this analysis revealed that SC diverged into various subgroups. Most were unique to Myanmar, while one was widespread in South China and southeastern Asia, including Myanmar. The present findings are consistent with the view that Myanmar was established by waves of human migration from neighboring regions

Archaeology · Biology · China · Gene · Genotype · Genotyping · Geography · JC virus · Phylogenetic tree · Progressive multifocal leukoencephalopathy · Virus · Plant Virus Research Studies · Polyomavirus and related diseases · Viral Infections and Outbreaks Research · Genetics · Virology