Findings from the Tushirikiane-4-MH (supporting each other for mental health) mobile health–supported virtual reality randomized controlled trial among urban refugee youth in Kampala, Uganda

Virtual reality (VR) for mental health promotion remains understudied in low-income humanitarian settings. We examined the effectiveness of VR in reducing depression with urban refugee youth in Kampala, Uganda. This randomized controlled trial assessed VR alone (Arm 1), VR followed by Group Problem Management Plus (GPM+) (Arm 2) and a control group (Arm 3), with a peer-driven and convenience sample of refugee youth aged 16–25 in Kampala. The primary outcome, depression, was measured with the Patient Health Questionnaire-9. Secondary outcomes included: mental health literacy, mental health stigma, self-compassion, mental well-being and adaptive coping. Analyses were conducted at three time points (baseline, 8 weeks, 16 weeks) using generalized estimating equations. Among participants ( n = 335, mean age: 20.77, standard deviation: 3.01; cisgender women: n = 158, cisgender men: n = 173, transgender women: n = 4), we found no depression reductions for Arms 1 or 2 at 16 weeks compared with Arm 3. At 16 weeks, mental health literacy was significantly higher for Arm 2 compared with Arm 3, and self-compassion was significantly higher in Arm 1 and Arm 2 compared with Arm 3. VR alongside GPM+ may benefit self-compassion and MHL among urban refugee youth in Kampala, but these interventions were not effective in reducing depression

Mental health · Political science · Psychiatry · Randomized controlled trial · Refugee · Digital Mental Health Interventions · Medicine · Migration, Health and Trauma · Psychology · Telemedicine and Telehealth Implementation

• Findings from the Tushirikiane-4-MH (supporting each other for mental health) mobile health–supported virtual reality randomized controlled trial among urban refugee youth in Kampala, Uganda

  Open Access•Carmen H Logie, Moses Okumu et al.•Cambridge Prisms Global Mental…•2025

  Incluir item

• The history, geography, and sociology of slums and the health problems of people who live in slums

  Open Access•Alex Ezeh, Oyinlola Oyebode et al.•The Lancet•2017

  Incluir item

• The Health Stigma and Discrimination Framework

  Open Access•Anne Stangl, Valerie A Earnshaw et al.•BMC Medicine•2019

  Incluir item

• Self‐Compassion, Self‐Esteem, and Well‐Being

  Open Access•Kristin D Neff•Social and Personality Psychology…•2011

  Incluir item

• Measuring well‐being rather than the absence of distress symptoms

  Open Access•Per Bech, Lis Raabaek Olsen et al.•International Journal of Methods…•2003

  Incluir item

• Development of a Brief Coping Checklist for Use with Pediatric Populations

  Anthony Spirito, Lori J Stark et al.•Journal of Pediatric Psychology•1988

  Incluir item

• Regression Analysis for Correlated Data

  K Y Liang, Kung‐Yee Liang et al.•Annual Review of Public Health•1993

  Incluir item

• Evidence for effective interventions to reduce mental health-related stigma and discrimination in the medium and long term

  Open Access•N Mehta, S Clement et al.•The British Journal of Psychiatry•2015

  Incluir item

• Problem Management Plus (PM+)

  Open Access•Katie S Dawson, Rebecca A Bryant et al.•World Psychiatry•2015

  Incluir item

• Effectiveness of a brief behavioural intervention on psychological distress among women with a history of gender-based violence in urban Kenya

  Open Access•Rebecca A Bryant, Alison Schafer et al.•PLoS Medicine•2017

  Incluir item

• A tutorial on sensitivity analyses in clinical trials

  Open Access•Lehana Thabane, Lawrence Mbuagbaw et al.•BMC Medical Research Methodology•2013

  Incluir item

• The contemporary refugee crisis

  Open Access•Derrick Silove, Peter Ventevogel et al.•World Psychiatry•2017

  Incluir item

• Interventions for Depression Symptoms Among Adolescent Survivors of War and Displacement in Northern Uganda

  Paul Bolton, Jeffrey Ba et al.•JAMA•2007

  Incluir item

• Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1)

  Open Access•Richard T Lester, Richard Lester et al.•The Lancet•2010

  Incluir item

• Mental Health Literacy

  Open Access•Stan Kutcher, Yifeng Wei et al.•The Canadian Journal of Psychiatry•2016

  Incluir item

• Longitudinal data analysis using generalized linear models

  Kung-Yee Liang, Kung‐Yee Liang et al.•Biometrika•1986

  Incluir item

• The socio-economic and psychosocial impact of Covid-19 pandemic on urban refugees in Uganda

  Open Access•Paul Bukuluki, Hadijah Mwenyango et al.•Social Sciences & Humanities Open•2020

  Incluir item

• Stop ‘controlling’ for sex and gender in global health research

  Open Access•Janna R Shapiro, Sabra L Klein et al.•BMJ Global Health•2021

  Incluir item

• Development and Validation of the Self-Compassion Scale for Youth

  Kristin D Neff, Karen Bluth et al.•Journal of Personality Assessment•2021

  Incluir item

• Mental health risks and stressors faced by urban refugees

  Open Access•Hyojin Im, Aidan Ferguson et al.•International Journal of Social…•2017

  Incluir item

• Experiences of gender-based stigma and health care-related outcomes in the African region

  Carmen H Logie, Valerie A Earnshaw et al.•Stigma and Health•2024

  Incluir item

• Contextual factors associated with depression among urban refugee and displaced youth in Kampala, Uganda

  Open Access•Carmen H Logie, Moses Okumu et al.•Conflict and Health•2020

  Incluir item

• Group problem management plus (gPM+) in the treatment of common mental disorders in Syrian refugees in a Jordanian camp

  Open Access•Aemal Akhtar, Luana Giardinelli et al.•BMC Public Health•2020

  Incluir item

• Physical fitness and mental health impact of a sport-for-development intervention in a post-conflict setting

  Open Access•Justin Richards, Charlie Foster et al.•BMC Public Health•2014

  Incluir item

• An Expanded Definition of Intersectional Stigma for Public Health Research and Praxis

  Kirsty M Sievwright, Kirsty Sievwright et al.•American Journal of Public Health•2022

  Incluir item

• Adolescent views of mental illness stigma

  Open Access•Melissa J Dupont-Reyes, A P Villatoro et al.•American Journal of Orthopsychiatry•2020

  Incluir item

• Mental health literacy

  Anthony F Jorm•American Psychologist•2011

  Incluir item

• Findings from the Tushirikiane-4-MH (supporting each other for mental health) mobile health–supported virtual reality randomized controlled trial among urban refugee youth in Kampala, Uganda

  Open Access•Carmen H Logie, Moses Okumu et al.•Cambridge Prisms Global Mental…•2025

  Incluir item

• Self-Compassion

  Kristin D Neff•Self and Identity•2003

  Incluir item