Taste-Aversion Conditioning, But Not Immunosuppression Conditioning, Occurs Under Partial Water Deprivation
Bibliographic Data
| ID | 10120609 |
|---|---|
| Authors | José VIDAL (0000-0001-5667-4133, Universitat Autonòma de Barcelona, corresponding author), V D Chamizo (0000-0001-7633-905X, Universitat de Barcelona) |
| Year | 2008 |
| Volume | 136 |
| Issue | 1 |
| Pages | 71-90 |
| Publication date | 2008-12-17 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | The Journal of General Psychology (JOURNAL) |
| Journal identifiers | ISSN: 0022-1309 • E-ISSN: 1940-0888 |
| Publisher | Taylor & Francis (PUBLISHER • GB) |
| DOI | 10.3200/genp.136.1.71-90 |
| PMID | 19192851 |
| OpenAlex | W1987745308 |
| Language | EN |
| References cited | 4 |
The authors investigated whether conditioned taste aversion and immunosuppression took place when water was available during conditioning and test protocols. The authors elicited taste-aversion conditioning and immunosuppression in outbred CD1-strain mice by pairing a conditioned stimulus (sucrose or saccharin solution) with an unconditioned stimulus (cyclophosphamide) that causes gastrointestinal upset and is immunosuppressive. The authors introduced a new conditioning protocol: 5 pairings of a saccharin solution with a low-dose injection of cyclophosphamide. Under these conditions, the authors generated conditioned aversion to saccharin but did not generate conditioned decrease of the antibody response. The authors conclude that taste-aversion conditioning, but not immunosuppression conditioning, occurred under partial water deprivation
Chemotherapy · Classical conditioning · Conditioning · Cyclophosphamide · Immunosuppression · Saccharin · Taste · Taste aversion · Unconditioned stimulus · Biochemical Analysis and Sensing Techniques · Endocrinology · Immune Cell Function and Interaction · Internal Medicine · Mathematics · Medicine · Neuroscience · Psychology
| Citation velocity | historical |
|---|---|
| Highly cited | No |