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Folic acid and neural tube defect

Can't we come to closure

Bibliographic Data

ID11018261
AuthorsWalter C Willett (0000-0003-1458-7597, corresponding author)
Year1992
Volume82
Issue5
Pages666-668
Publication date1992-05-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.82.5.666
PMID1566943
OpenAlexW2139769654
LanguageCA
Citations received1

In a series of nonrandomized and randomized intervention trials and case-control and cohort studies, women using multivitamins or folic acid supplements during the first 6 weeks of pregnancy experienced a three- to fourfold reduction in neural tube defects among their offspring. Viewed collectively, these data provide strong evidence that an important subset of US women do not receive sufficient folic acid to minimize their risk of a defective pregnancy. Further, the amounts of folic acid contained in multivitamins (usually 200-400 micrograms per day) appear adequate to greatly reduce, and probably eliminate, the excess risk

Biology · Cohort · folic acid · Folic acid supplementation · Neural tube · Neural tube defect · Obstetrics · Offspring · Pregnancy · Randomized controlled trial · Folate and B Vitamins Research · Internal Medicine · Medicine · Pregnancy and Medication Impact · Pregnancy and preeclampsia studies

  • Neural tube defects in Jamaica following Hurricane Gilbert

    E M Duff, Vanessa El Khoury et al.•American Journal of Public Health•1994

Unique citing works1
Citations per year0,03
Citation span1994 - 1994 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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