Enhancing Methodological Approaches for Studying Health Effects of High-Concentration THC Products

Bibliographic Data

ID11022396
AuthorsTianjing Li (0009-0009-5554-1721, Tianjing Li is with the Department of Ophthalmology, School of Medicine, University of Colorado Anschutz Medical Campus, and Department of Epidemiology, Colorado School of Public Health, Aurora. George Sam Wang is with the Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus. Lisa Bero is with the Center for Bioethics and Humanities, School of Medicine, University of Colorado Anschutz Medical Campus. Ashley Brooks-Russell is with the Department of Community and...), George Sam Wang (0000-0002-2931-3508, Tianjing Li is with the Department of Ophthalmology, School of Medicine, University of Colorado Anschutz Medical Campus, and Department of Epidemiology, Colorado School of Public Health, Aurora. George Sam Wang is with the Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus. Lisa Bero is with the Center for Bioethics and Humanities, School of Medicine, University of Colorado Anschutz Medical Campus. Ashley Brooks-Russell is with the Department of Community and...), Lisa Bero (0000-0003-1893-6651, Tianjing Li is with the Department of Ophthalmology, School of Medicine, University of Colorado Anschutz Medical Campus, and Department of Epidemiology, Colorado School of Public Health, Aurora. George Sam Wang is with the Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus. Lisa Bero is with the Center for Bioethics and Humanities, School of Medicine, University of Colorado Anschutz Medical Campus. Ashley Brooks-Russell is with the Department of Community and...), Ashley Brooks-Russell (0000-0002-7728-8423, Tianjing Li is with the Department of Ophthalmology, School of Medicine, University of Colorado Anschutz Medical Campus, and Department of Epidemiology, Colorado School of Public Health, Aurora. George Sam Wang is with the Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus. Lisa Bero is with the Center for Bioethics and Humanities, School of Medicine, University of Colorado Anschutz Medical Campus. Ashley Brooks-Russell is with the Department of Community and...), Gregory Tung (Tianjing Li is with the Department of Ophthalmology, School of Medicine, University of Colorado Anschutz Medical Campus, and Department of Epidemiology, Colorado School of Public Health, Aurora. George Sam Wang is with the Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus. Lisa Bero is with the Center for Bioethics and Humanities, School of Medicine, University of Colorado Anschutz Medical Campus. Ashley Brooks-Russell is with the Department of Community and...), Jonathan M Samet (0000-0001-5676-9175, Tianjing Li is with the Department of Ophthalmology, School of Medicine, University of Colorado Anschutz Medical Campus, and Department of Epidemiology, Colorado School of Public Health, Aurora. George Sam Wang is with the Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus. Lisa Bero is with the Center for Bioethics and Humanities, School of Medicine, University of Colorado Anschutz Medical Campus. Ashley Brooks-Russell is with the Department of Community and...)
Year2024
Volume114
IssueS8
PagesS639-S644
Publication date2024-11-01
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.2024.307724
PMID39442035
OpenAlexW4403665869
LanguageEN
References cited14

For public health protection, informed decision-making relies on having a robust foundation of evidence concerning risks and their prevention. Application of an evidence-based framework depends on the availability of pertinent, scientifically sound data generated by well-directed and valid research endeavors. In this essay, we address the current state of research in humans and the evidential base concerning high-concentration delta-9-tetrahydrocannabinol (delta-9-THC) products, which are readily available in the United States. Furthermore, we explore the intricate challenges faced in carrying out research on these products, which reflect the full range of study design issues: measurement of exposure and outcomes, confounding, selection bias, and the generalizability of findings. We offer recommendations to guide future research toward providing more informative evidence. By following these recommendations, researchers and funders on this emerging topic could move toward generating the valid and comprehensive evidence needed to effectively inform public health initiatives and guide policy decisions regarding high-concentration delta-9-THC products and their use. The urgency of generating such evidence cannot be overstated, given the widespread legalization and increasing availability and use of these products. ( Am J Public Health. 2024;114(S8):S639–S644. https://doi.org/10.2105/AJPH.2024.307724 )

Alternative medicine · Comparability · Economics · Environmental health · Evidence-based policy · Evidence-based practice · Foundation (evidence) · Generalizability theory · Management science · Political science · Public economics · Public health · Public relations · Cannabis and Cannabinoid Research · Carcinogens and Genotoxicity Assessment · Law · Medicine · Psychology · Smoking Behavior and Cessation

Tools

Open DOIOpen Access