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Ashkenazi Jews and Breast Cancer

The Consequences of Linking Ethnic Identity to Genetic Disease

Bibliographic Data

ID11028293
AuthorsSherry I Brandt-Rauf (Sherry I. Brandt-Rauf, Nathan F. Drummond, Jill A. Conte, and Sheila M. Rothman are with the Center for the Study of Society and Medicine, College of Physicians and Surgeons, Columbia University, New York, NY. Victoria H. Raveis is with the Center for the Psychosocial Study of Health and Illness, Mailman School of Public Health, Columbia University. Sheila M. Rothman is also with the Mailman School of Public Health.), Victoria H Raveis (0000-0001-6063-7669, Sherry I. Brandt-Rauf, Nathan F. Drummond, Jill A. Conte, and Sheila M. Rothman are with the Center for the Study of Society and Medicine, College of Physicians and Surgeons, Columbia University, New York, NY. Victoria H. Raveis is with the Center for the Psychosocial Study of Health and Illness, Mailman School of Public Health, Columbia University. Sheila M. Rothman is also with the Mailman School of Public Health.), Nathan F Drummond (Sherry I. Brandt-Rauf, Nathan F. Drummond, Jill A. Conte, and Sheila M. Rothman are with the Center for the Study of Society and Medicine, College of Physicians and Surgeons, Columbia University, New York, NY. Victoria H. Raveis is with the Center for the Psychosocial Study of Health and Illness, Mailman School of Public Health, Columbia University. Sheila M. Rothman is also with the Mailman School of Public Health.), Jill A Conte (Sherry I. Brandt-Rauf, Nathan F. Drummond, Jill A. Conte, and Sheila M. Rothman are with the Center for the Study of Society and Medicine, College of Physicians and Surgeons, Columbia University, New York, NY. Victoria H. Raveis is with the Center for the Psychosocial Study of Health and Illness, Mailman School of Public Health, Columbia University. Sheila M. Rothman is also with the Mailman School of Public Health.), Jill Conte (0000-0002-3324-6707, Rothman Orthopaedics), Sheila M Rothman (Sherry I. Brandt-Rauf, Nathan F. Drummond, Jill A. Conte, and Sheila M. Rothman are with the Center for the Study of Society and Medicine, College of Physicians and Surgeons, Columbia University, New York, NY. Victoria H. Raveis is with the Center for the Psychosocial Study of Health and Illness, Mailman School of Public Health, Columbia University. Sheila M. Rothman is also with the Mailman School of Public Health.)
Year2006
Volume96
Issue11
Pages1979-1988
Publication date2006-11-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.2005.083014
PMID17018815
PMCIDPMC1751808
OpenAlexW2052856270
LanguageEN
Citations received6
References cited111

We explored the advantages and disadvantages of using ethnic categories in genetic research. With the discovery that certain breast cancer gene mutations appeared to be more prevalent in Ashkenazi Jews, breast cancer researchers moved their focus from high-risk families to ethnicity. The concept of Ashkenazi Jews as genetically unique, a legacy of Tay–Sachs disease research and a particular reading of history, shaped this new approach even as methodological imprecision and new genetic and historical research challenged it. Our findings cast doubt on the accuracy and desirability of linking ethnic groups to genetic disease. Such linkages exaggerate genetic differences among ethnic groups and lead to unequal access to testing and therapy

Breast cancer · Cancer · Disease · Ethnic group · Identity (music) · Sociology · Anthropology · BRCA gene mutations in cancer · Demography · Genomic variations and chromosomal abnormalities · Internal Medicine · Medicine · Race, Genetics, and Society

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Unique citing works6
Citations per year0,38
Citation span2010 - 2017 (8)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 6

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