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Risk factors for HIV-1 seroconversion among injection drug users

A case-control study

Bibliographic Data

ID11028692
AuthorsDale D Chitwood (Sylvester Comprehensive Cancer Center), David Griffin (0000-0001-8077-8610, University of Miami), D K Griffin, Mary Comerford (University of Miami), J Bryan Page (University of Miami), Edward Trapido (0000-0002-9612-4555, University of Miami), E J Trapido, Shenghan Lai (0000-0003-1340-9609, University of Miami), Clyde B Mccoy (Faculty of Public Health)
Year1995
Volume85
Issue11
Pages1538-1542
Publication date1995-11-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.85.11.1538
PMID7485667
OpenAlexW2089914402
LanguageEN
Citations received15
References cited28

OBJECTIVES. A nested case-control study was conducted in Miami, Fla, to determine risk factors associated with human immunodeficiency virus type 1 (HIV-1) seroconversion among injection drug users. METHODS. The study identified 21 incident cases of HIV-1 infection and 76 unmatched controls from two longitudinal cohorts of injection drug users. One cohort consisted of individuals who originally had been recruited from treatment centers; a second cohort was recruited from the "street." Logistic regression analyses that adjusted for age, gender, and race were performed. RESULTS. The final model determined that the primary independent risk factor that best explained the risk for seroconversion was sharing injection equipment in the year prior to conversion; a marginal risk factor was presence of sexually transmitted disease during this same period. CONCLUSIONS. Both an injection component and a sexual component play a role in seroconversion among injection drug users, although the injection component is much stronger

Cohort · Cohort study · Drug injection · Human immunodeficiency virus (HIV) · Logistic regression · Risk factor · Seroconversion · Demography · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Immunology · Internal Medicine · Medicine · Sex work and related issues

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Unique citing works15
Citations per year0,52
Citation span1997 - 2022 (26)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 15

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