Primary HIV infection--a public health opportunity
Bibliographic Data
| ID | 11028883 |
|---|---|
| Authors | W Cates (Family Health International 360), Margaret A Chesney (0000-0001-6038-3486, University of California, San Francisco), Myron S Cohen (0000-0001-5917-9664, Office of Infectious Diseases) |
| Year | 1997 |
| Volume | 87 |
| Issue | 12 |
| Pages | 1928-1930 |
| Publication date | 1997-12-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | American Journal of Public Health (JOURNAL) |
| Journal identifiers | ISSN: 0090-0036 • E-ISSN: 1541-0048 |
| Publisher | American Public Health Association (PUBLISHER • US) |
| DOI | 10.2105/ajph.87.12.1928 |
| PMID | 9431278 |
| OpenAlex | W2164130077 |
| Language | EN |
| Citations received | 7 |
| References cited | 22 |
Primary human immunodeficiency virus (HIV) infection should be considered a key target for HIV prevention activities. Mathematical models suggest that the primary HIV infection interval makes a disproportionate contribution to the HIV epidemic, perhaps accounting for as many as half of the existing infections at any point in time. If this is true, primary infection presents a special window of opportunity within which to exert a maximum impact on the spread of HIV. A combination of biological, behavioral, and social factors may account for the influence of primary infection on the HIV epidemic. HIV prevention measures can be focused on each of these factors. Biologically, detecting individuals early in the course of infection and offering treatment can reduce viral load and possibly an individual's infectiousness. Behaviorally, counseling newly infected persons about the importance of adopting safer practices may instill prevention behaviors at a critical time. Socially, using a network approach to notify persons exposed to those with primary infections can dampen the amplification effect of rapid HIV spread through high-risk environments. By focusing prevention efforts on the primary HIV infection interval, public health officials could increase their leverage in slowing the HIV epidemic
Disease · Environmental health · Human immunodeficiency virus (HIV) · Leverage (statistics) · Primary prevention · Public health · Window of opportunity · Adolescent Sexual and Reproductive Health · HIV Research and Treatment · HIV/AIDS Research and Interventions · Immunology · Internal Medicine · Medicine · Nursing · Virology
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| Unique citing works | 7 |
|---|---|
| Citations per year | 0,27 |
| Citation span | 2000 - 2015 (16) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 6 |