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Risk for neural tube defect-affected pregnancies among women of Mexican descent and white women in California

Bibliographic Data

ID11030252
AuthorsGary M Shaw (0000-0001-7438-4914, March of Dimes), Ellen M Velie (0000-0001-6865-9715), Cathy R Wasserman
Year1997
Volume87
Issue9
Pages1467-1471
Publication date1997-09-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.87.9.1467
PMID9314798
OpenAlexW2050432165
LanguageEN
Citations received5
References cited15

OBJECTIVES: This study investigated a previously reported 50% or more increased risk for neural tube defect-affected pregnancies among Latina women compared with White women. METHODS: Data were derived from a population-based case-control study of fetuses and live-born infants with neural tube defects in a 1989-through-1991 California birth cohort. Interviews were conducted with mothers of 538 (88% of eligible) infants/fetuses with neural tube defects and mothers of 539 (88%) nonmalformed control infants. RESULTS: The risk for a neural tube defect-affected pregnancy was approximately twice as high among women of Mexican descent than among White women (odds ratio = 1.9, 95% confidence interval [CI] = 1.5, 2.8). The odds ratio for Mexico-born Mexican women compared with White women was 2.4 (95% CI = 1.7, 3.2), whereas the risk for US-born women of Mexican and other racial/ethnic descent was not substantially higher than that for Whites. The higher risk among Mexico-born Mexican women was not attributable to differences in numerous studied parental characteristics and exposures. CONCLUSIONS: Given that nearly 20% of all California births are to Mexico-born Mexican women, the increased risks observed are relevant to the population burden of neural tube defects

Anencephaly · Biology · Confidence interval · Environmental health · Fetus · Neural tube · Neural tube defect · Obstetrics · Odds ratio · Population · Pregnancy · Relative risk · Demography · Folate and B Vitamins Research · Internal Medicine · Medicine · Prenatal Screening and Diagnostics · Spinal Dysraphism and Malformations · Pediatrics

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Unique citing works5
Citations per year0.21
Citation span2002 - 2019 (18)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 4

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