The effects of acute plasma tryptophan manipulation on hostile mood
The influence of trait hostility
Bibliographic Data
| ID | 11106934 |
|---|---|
| Authors | Peter R Finn, Peter Finn (0000-0002-0998-0442, Indiana University Bloomington, corresponding author), Simon N Young (0000-0001-9666-8096, McGill University), Robert O Pihl (McGill University), Frank R Ervin (McGill University) |
| Year | 1998 |
| Volume | 24 |
| Issue | 3 |
| Pages | 173-185 |
| Publication date | 1998-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Aggressive Behavior (JOURNAL) |
| Journal identifiers | ISSN: 0096-140X • E-ISSN: 1098-2337 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/(sici)1098-2337(1998)24:3<173::aid-ab2>3.0.co;2-m |
| OpenAlex | W1986902884 |
| Language | EN |
| References cited | 35 |
The effects of acute plasma tryptophan manipulation on changes in hostile, anxious, and depressive mood were studied in 48 males. Subjects consumed tryptophan-free or nutritionally balanced amino acid mixtures as a means of manipulating brain serotonin levels. Mood (hostility, anxiety, depression) was assessed pre- and 5 hr post-ingestion using the Multiple Affect Adjective Checklist. Overall, the tryptophan manipulation resulted in significant changes in hostile mood. Analyses also revealed a stronger association between changes in plasma tryptophan and changes in hostility in subjects with high levels of pre-existing hostile traits compared with low levels of hostile traits, and in subjects with high vs. Low antisocial traits. There was no significant association between changes in plasma tryptophan and changes in depression. The results suggest that persons with high levels of trait hostility may be more susceptible to the effects of acute manipulation of plasma tryptophan on hostile mood. Aggr. Behav. 24:173–185, 1998. © 1998 Wiley-Liss, Inc.
Adjective check list · Affect (linguistics) · Amino acid · Anxiety · Depression (economics) · Hostility · Medical emergency · Mood · Personality · Poison control · Psychiatry · Serotonin · Trait · Tryptophan · Biochemistry · Bipolar Disorder and Treatment · Chemistry · Clinical Psychology · Endocrinology · Internal Medicine · Medicine · Neurotransmitter Receptor Influence on Behavior · Psychology · Social Psychology · Tryptophan and brain disorders
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| Citation velocity | historical |
|---|---|
| Highly cited | No |