The medial amygdala
Serotonergic inhibition of shock-lnduced aggression and pain sensitivity in rats
Bibliographic Data
| ID | 11107689 |
|---|---|
| Authors | R J Rodgers (University of Bradford, corresponding author) |
| Year | 1977 |
| Volume | 3 |
| Issue | 3 |
| Pages | 277-288 |
| Publication date | 1977-01-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Aggressive Behavior (JOURNAL) |
| Journal identifiers | ISSN: 0096-140X • E-ISSN: 1098-2337 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/1098-2337(1977)3:3<277::aid-ab2480030309>3.0.co;2-5 |
| OpenAlex | W2061770311 |
| Language | EN |
| Citations received | 1 |
| References cited | 56 |
Two aspects of the amygdaloid complex (corticomedial and basolateral) were examined with reference to serotonergic inhibition of shock-induced aggression. Fighting was significantly depressed by serotonergic stimulation (5-HT, 10 μg bilateral) in the corticomedial amygdala while serotonergic blockade (methysergide, 5 μg bilateral) in this region increased levels of fighting. No consistent effects were obtained with serotonergic manipulation of the basolateral amygdala. Further investigation revealed that the state of serotonergic activity in medial amygdaloid sites was associated with concomitant alterations in the animals' sensitivity to footshock. Results are discussed in relation to a) a general inhibitory role of serotonin in behavioural mechanisms and b) a dopaminergic-serotonergic balance for behavioural arousal involving medial amygdaloid nuclei.
Aggression · Amygdala · Anesthesia · Psychiatry · Sensitivity (control systems) · Serotonergic · Serotonin · Shock (circulatory) · Clinical Psychology · Internal Medicine · Medicine · Neuroendocrine regulation and behavior · Neuropeptides and Animal Physiology · Neuroscience · Neurotransmitter Receptor Influence on Behavior · Psychology
| Citations per year | 0.02 |
|---|---|
| Citation span | 1979 - 1979 (1) |
| Highly cited | No |