Framing a Consent Form to Improve Consent Understanding and Determine How This Affects Willingness to Participate in HIV Cure Research
An Experimental Survey Study
Bibliographic Data
| ID | 12807093 |
|---|---|
| Authors | John A Sauceda (0000-0003-1975-3080, University of California, San Francisco, corresponding author), Karine Dubé (0000-0003-3458-1539, University of North Carolina at Chapel Hill), Brandon Brown (0000-0002-6348-4108, University of California, Riverside), Ashley E Pérez (0000-0003-2746-561X, University of California, San Francisco), Catherine E Rivas (University of California, San Francisco), David Evans (0000-0001-7258-3485, Delaney AIDS Research Enterprise), Celia B Fisher (0000-0002-3849-7281, Fordham University) |
| Year | 2020 |
| Volume | 16 |
| Issue | 1-2 |
| Pages | 78-87 |
| Publication date | 2020-12-14 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Empirical Research on Human Research Ethics (JOURNAL) |
| Journal identifiers | ISSN: 1556-2646 • E-ISSN: 1556-2654 |
| Publisher | SAGE Publishing (PUBLISHER • US) |
| DOI | 10.1177/1556264620981205 |
| PMID | 33307932 |
| OpenAlex | W3112374473 |
| Language | EN |
| Citations received | 3 |
| References cited | 35 |
HIV cure research carries serious risks and negligible benefits. We investigated how participants understand these risks and what influences their willingness to participate. Through internet-based and in-person convenience sampling, 86 HIV+ participants completed an experimental survey. Participants were randomized to read a standard consent form describing a hypothetical HIV cure study or one adapted using Fuzzy Trace Theory-a decision-making model to facilitate complex information processing. We measured consent understanding and cognitive (e.g., safe/harmful) and affective (e.g., concerning, satisfying) evaluations of HIV cure research. Participants who read the adapted consent form had improved consent understanding, but only positive affective evaluations were associated with a willingness to participate. Consent processes can use decision-making theories to facilitate comprehension of study information
Alternative medicine · Cognition · Comprehension · Framing (construction · Informed consent · Psychiatry · Clinical Psychology · Computer Science · Ethics in Clinical Research · Medicine · Patient-Provider Communication in Healthcare · Psychology · Psychology of Moral and Emotional Judgment · Social Psychology
Competence to Consent and Willingness to Participate in Behavioral Trials Among a Mixed HIV Serostatus Sample of Young Gay and Bisexual Men Who Use Stimulants
Evaluating the psychosocial experiences of participants in HIV cure research before, during, and after analytical treatment interruptions
Recall and Appraisal of the Risks, Benefits, and Objectives of Interrupting HIV Treatment in an HIV Cure-Related Study
Measuring the Affective and Cognitive Properties of Attitudes
A Theory of Medical Decision Making and Health
A New Brief Instrument for Assessing Decisional Capacity for Clinical Research
How People Make Decisions That Involve Risk
A measure of informed choice
Cure” Versus “Clinical Remission”
Misunderstanding in Clinical Research
Perceptions of Equipoise, Risk–Benefit Ratios, and “Otherwise Healthy Volunteers” in the Context of Early-Phase HIV Cure Research in the United States
Are Well-Informed Potential Trial Participants More Likely to Participate
Fuzzy‐trace theory and framing effects in choice
Beyond Baron and Kenny
Forming attitudes that predict future behavior
| Citations per year | 1.5 |
|---|---|
| Citation span | 2024 - 2026 (3) |
| Highly cited | No |