Effects of Hippocampal, Amygdala, Hypothalamic and Parietal Lesions on a Classically Conditioned Fear Response

Bibliographic Data

ID13657830
AuthorsMELVIN L GOLDSTEIN (University of Wisconsin)
Year1965
Volume16
Issue1
Pages211-219
Publication date1965-02-01
Open AccessYes
TypeARTICLE
VenuePsychological Reports (JOURNAL)
Journal identifiersISSN: 0033-2941 • E-ISSN: 1558-691X
PublisherSAGE Publishing (PUBLISHER • US)
DOI10.2466/pr0.1965.16.1.211
PMID14283965
OpenAlexW2129497811
LanguageEN
Citations received6
References cited12

Experiments investigating the effects of limbic system lesions in a modified classical conditioning situation were performed on 68 rats. Pre- and post-operative tests were given to parietal and amygdalectomized Ss. Postoperative tests were given to parietal, hippocampal, and amygdalectomized Ss. Hypothalamic and amygdaloid Ss showed no evidence of learning the test response. Contrary to previous reports, it was found that animals with small hippocampal lesions were able to learn the test response. The observed learning deficits were discussed in terms of possible receptor mechanisms for painful stimuli controlled by basolateral amygdaloid nucleus and ventromedial hypothalamus

Amygdala · Basolateral amygdala · Fear conditioning · Fear processing in the brain · Hippocampal formation · Hippocampus · Memory and Neural Mechanisms · Neuroscience · Neuroscience and Neuropharmacology Research · Psychology · Stress Responses and Cortisol

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