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Changes in Locomotor Activity and Brain Chemistry following LSD-25 Administration in Mice

Bibliographic Data

ID13665237
AuthorsWalter B Essman (Queens College of the City University of New York, corresponding author)
Year1967
Volume20
Issue1
Pages124-126
Publication date1967-02-01
Open AccessYes
TypeARTICLE
VenuePsychological Reports (JOURNAL)
Journal identifiersISSN: 0033-2941 • E-ISSN: 1558-691X
PublisherSAGE Publishing (PUBLISHER • US)
DOI10.2466/pr0.1967.20.1.124
PMID6037771
OpenAlexW2314740732
LanguageEN
References cited2

Mice treated with LSD-25 showed a marked attenuation of gross locomotor activity by 15 min. following injection, as compared with saline-treated controls. This effect was paralleled by intracerebral injection of adrenochrome; the level of brain adrenochrome was elevated in LSD-treated mice and correlated with the attenuated locomotor activity

Adrenochrome · Epinephrine · Locomotor activity · Saline · Biochemical effects in animals · Chemistry · Endocrinology · Medicine · Neuroscience · Pharmacology · Psychology

Highly citedNo

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