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A Pilot Study Comparing a Community of Practice Program with and without Concurrent Ketamine-Assisted Therapy

Bibliographic Data

ID13914280
AuthorsVivian W L Tsang (0000-0001-9401-008X, Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada, corresponding author), Dragos C Ragazan (0000-0002-8953-3991, University of British Columbia), Pamela Kryskow (0000-0003-0310-0368, Health and Human Services, Vancouver Island University, Nanaimo, BC, Canada), Zach Walsh (University of British Columbia), Shannon Dames (0000-0003-1609-4243, Health and Human Services, Vancouver Island University, Nanaimo, BC, Canada)
Year2023
Volume56
Issue5
Pages627-636
Publication date2023-09-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueJournal of Psychoactive Drugs (JOURNAL)
Journal identifiersISSN: 0279-1072 • E-ISSN: 2159-9777
PublisherTaylor & Francis (PUBLISHER • GB)
DOI10.1080/02791072.2023.2253798
PMID37655532
OpenAlexW4386346817
LanguageEN
Citations received4
References cited61

The prevalence of depression, anxiety, and post-traumatic stress disorder (PTSD) has increased among healthcare providers, while the effectiveness of conventional treatments remains limited. Ketamine-assisted therapy offers a promising alternative; however, few have integrated ketamine with a group-based therapeutic modality. We report a retrospective, secondary analysis of a 12-week pilot of a Community of Practice (CoP) oriented group therapy program with optional, adjunct ketamine for depression, anxiety, and PTSD in a sample of 57 healthcare providers. All participants moved through the treatment as one group, with 38 electing to also receive three adjunct ketamine sessions in addition to the weekly CoP. Symptoms were assessed at baseline and pilot completion with the PHQ-9 for depression, GAD-7 for anxiety, and PCL-5 for PTSD. We observed significant reductions in the mean change among all participants, suggesting that benefit was derived from the CoP component, with or without ketamine as an adjunct. PHQ-9 scores decreased by 6.79 (95% CI: 5.09-8.49, p p p < .001). Reductions were larger, but statistically nonsignificant, among those receiving ketamine. Further research is required to assess the impact of ketamine as an adjunct in group-based therapies

Adjunct · Anxiety · Depression (economics · Ketamine · Physical therapy · Psychiatry · Medicine · Mental Health Treatment and Access · Treatment of Major Depression · Tryptophan and brain disorders

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Unique citing works4
Citations per year2
Citation span2024 - 2026 (3)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 4

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