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Genetic admixture history and forensic characteristics of Turkic-speaking Kyrgyz population via 23 autosomal STRs

Bibliographic Data

ID13922352
AuthorsPengyu Chen (0000-0003-4584-2036, Center of Forensic Expertise, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China;), Xing Zou (0009-0006-8632-1770, Sichuan University), Biao Wang (0000-0002-8655-6258, Institute of Forensic Science), Mengge Wang (0000-0002-3673-1855, Sichuan University, corresponding author), Guanglin He (0000-0002-6614-5267, Sichuan University, corresponding author)
Year2019
Volume46
Issue6
Pages498-501
Publication date2019-08-18
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAnnals of Human Biology (JOURNAL)
Journal identifiersISSN: 0301-4460 • E-ISSN: 1464-5033
PublisherInforma (PUBLISHER • GB)
DOI10.1080/03014460.2019.1676918
PMID31665944
OpenAlexW2987521049
LanguageEN
Citations received2
References cited18

Kyrgyz people, a Turkic-speaking ethnic group native to Central Asia, are considered as one mixed population from different historical tribes through the processes of conquest, intermarriage, assimilation and migration. The aim of this study was to infer the forensic statistical parameters and genetic structure of Chinese Kyrgyz and explore the patterns of their genetic relationships with adjacent and worldwide reference populations. We genotyped 25 forensic-related markers (amelogenin, Y-indel of rs2032678 and 23 Autosomal Short Tandem Repeats, A-STRs) in 491 Chinese Kyrgyzs. Allele frequency and forensic parameters were calculated using the STRAF software. Pairwise genetic distances were estimated using Phylip and subsequently dissected via principal component analysis, multidimensional scaling plots and phylogenetic relationship reconstruction. Investigations of allele frequency and forensic parameters indicated that all studied A-STRs are informative in the Chinese Kyrgyz population and can be used as a powerful tool in forensic individual identification and parentage testing. Results from genetic relationship analyses demonstrated that Akto Kyrgyz people harbour a genetically close relationship with Turkic-speaking Uyghur and Kazakh. Genetic structure analysis based on the raw genotype data among Eurasian populations further suggested that genetic ancestries and population substructures in Asia are largely associated with language and geography

Allele · Allele frequency · Biology · Evolutionary biology · Forensic identification · Forensic science · Gene · Genetic diversity · Genetic structure · Genetic variation · Genotype · Kazakh · Linguistics · Microsatellite · Phylogenetic tree · Population · Demography · Forensic and Genetic Research · Forensic Anthropology and Bioarchaeology Studies · Molecular Biology Techniques and Applications · Genetics

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Unique citing works2
Citations per year0,67
Citation span2023 - 2024 (2)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 2

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