Direct targeting of STAT3 by xanthatin suppresses allergic airway inflammation via inhibition of TSLP release and NK2 cell polarization
Bibliographic Data
Xanthatin ameliorates allergic airway inflammation by directly targeting STAT3, thereby dually inhibiting the TSLP/STAT3 axis in epithelial cells and the subsequent STAT3-dependent differentiation of pathogenic NK2 cells, presenting a promising multi-targeted strategy for asthma treatment
Airway · Allergic asthma · Allergic inflammation · Asthma · Inflammation · STAT3 · Polysaccharides and Plant Cell Walls · Polysaccharides Composition and Applications · Proteoglycans and glycosaminoglycans research
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