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Pharmacokinetics of artemisinin delivered by oral consumption of Artemisia annua dried leaves in healthy vs. Plasmodium chabaudi-infected mice

Bibliographic Data

ID14731935
AuthorsPamela J Weathers (0000-0001-5138-3839, corresponding author), Mostafa A Elfawal (University of Massachusetts Amherst), Melissa J Towler, George K Acquaah-Mensah (0000-0003-3984-8327), Stephen M Rich (0000-0001-7175-6380, University of Massachusetts Amherst)
Year2014
Volume153
Issue3
Pages732-736
Publication date2014-05-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2014.03.037
PMID24661969
PMCIDPMC4020007
OpenAlexW1997833445
LanguageEN
Citations received6
References cited27

Area under the curve · Artemisia annua · Artemisinin · Cmax · Elimination rate constant · Malaria · Oral administration · Parasitemia · Pharmacokinetics · Plasmodium chabaudi · Plasmodium falciparum · Chemistry · Malaria Research and Control · Medicine · Pharmacological Effects of Natural Compounds · Plant biochemistry and biosynthesis · Immunology · Pharmacology

  • Differential synergistic antimalarial effects of an A. annua extract on artemisinin via host pharmacokinetic modulation

    Open Access•Kun Xu, Yuewu Xie et al.•Journal of Ethnopharmacology•2026

  • Targeted screening of the synergistic components in Artemisia annua L. leading to enhanced antiplasmodial potency of artemisinin based on a "top down" PD-PK approach

    Open Access•Tian-Yu Cai, Tianyu Cai et al.•Journal of Ethnopharmacology•2024

  • Artemisia annua L. extracts inhibit the in vitro replication of Sars-CoV-2 and two of its variants

    Open Access•M S Nair, Yiming Huang et al.•Journal of Ethnopharmacology•2021

  • Artemisia extracts differ from artemisinin effects on human hepatic CYP450s 2B6 and 3A4 in vitro

    Open Access•Ndeye F Kane, Bushra Hafeez Kiani et al.•Journal of Ethnopharmacology•2022

  • Investigation of the component in Artemisia annua L. leading to enhanced antiplasmodial potency of artemisinin via regulation of its metabolism

    Open Access•Tian-Yu Cai, Tianyu Cai et al.•Journal of Ethnopharmacology•2017

  • Effect of leaf digestion and artemisinin solubility for use in oral consumption of dried Artemisia annua leaves to treat malaria

    Open Access•Matthew R Desrosiers, Pamela J Weathers•Journal of Ethnopharmacology•2016

  • Simulated digestion of dried leaves of Artemisia annua consumed as a treatment (pACT) for malaria

    Pamela J Weathers, Nikole J Jordan et al.•Journal of Ethnopharmacology•2014

  • Handbook of Phytochemical Constituents of GRAS Herbs and other Economic Plants

    Open Access•Michael Heinrich•Journal of Ethnopharmacology•2001

Citations per year0.6
Citation span2016 - 2026 (11)
Highly citedNo

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