Tiao Geng decoction for treating menopausal syndrome exhibits anti-aging effects likely via suppressing ASK1/MKK7/JNK mediated apoptosis in ovariectomized rats

Bibliographic Data

ID14733442
AuthorsShengnan Li (0000-0001-9021-5088, Shanghai University of Traditional Chinese Medicine), Chao Cong (Shanghai University of Traditional Chinese Medicine), Yang Liu (0000-0003-1220-7044, Longhua Hospital Shanghai University of Traditional Chinese Medicine), Xiaofei Liu (0000-0001-6720-644X, Longhua Hospital Shanghai University of Traditional Chinese Medicine), Lan Kluwe (0000-0001-9919-4551, University Medical Center Hamburg-Eppendorf), Xuemei Shan (0009-0000-8840-7312), Xin Shan (0000-0003-3775-0131, Longhua Hospital Shanghai University of Traditional Chinese Medicine), Huicong Liu (0000-0003-3651-9114, Shanghai University of Traditional Chinese Medicine), Min Gao (0000-0002-8253-0587, Longhua Hospital Shanghai University of Traditional Chinese Medicine), Li Zhao (0009-0004-7836-6878, Shanghai University of Traditional Chinese Medicine), Xianwei Gao (0000-0001-7391-6149, Shanghai University of Traditional Chinese Medicine), Lianwei Xu (0009-0004-2676-8912, Longhua Hospital Shanghai University of Traditional Chinese Medicine, corresponding author)
Year2020
Volume261
Pages113061
Publication date2020-10-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2020.113061
PMID32525065
OpenAlexW3033818988
LanguageEN
Citations received3
References cited20

TG-decoction reduces aging-related ultrastructural changes in hypothalamic neurons, likely by suppressing ASK1/MKK7/JNK-mediated apoptosis in neuronal mitochondria or nuclei

Apoptosis · Decoction · Estrogen · Immunohistochemistry · Lipofuscin · Nissl body · Ovariectomized rat · Oxidative stress · Pathology · Staining · TUNEL assay · Biological and pharmacological studies of plants · Chemistry · Medicine · Menopause: Health Impacts and Treatments · Pharmacological Effects of Natural Compounds · Biochemistry · Endocrinology · Internal Medicine

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