Tiao Geng decoction inhibits tributyltin chloride-induced GT1-7 neuronal apoptosis through ASK1/MKK7/JNK signaling pathway

Bibliographic Data

ID14733495
AuthorsShengnan Li (0000-0001-9021-5088, Shanghai University of Traditional Chinese Medicine), Chao Cong (Shanghai University of Traditional Chinese Medicine), Yang Liu (0000-0003-1220-7044, Shanghai University of Traditional Chinese Medicine), Xiaofei Liu (0000-0001-6720-644X, Longhua Hospital Shanghai University of Traditional Chinese Medicine), Huicong Liu (0000-0003-3651-9114, Longhua Hospital Shanghai University of Traditional Chinese Medicine), Li Zhao (0009-0004-7836-6878, Shanghai University of Traditional Chinese Medicine), Xianwei Gao (0000-0001-7391-6149, Shanghai University of Traditional Chinese Medicine), Wenjia Gui (Longhua Hospital Shanghai University of Traditional Chinese Medicine), Lianwei Xu (0009-0004-2676-8912, Shanghai University of Traditional Chinese Medicine, corresponding author)
Year2021
Volume269
Pages113669
Publication date2021-04-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2020.113669
PMID33338591
OpenAlexW3111831016
LanguageEN
Citations received1
References cited22

As discovered from the experiment in this study, TG decoction has a neuroprotective effect, which is achieved through inhibiting the ASK1/MKK7/JNK signal transduction pathway to reduce GT1-7 cell apoptosis

Apoptosis · ASK1 · Decoction · Kinase · Mitogen-activated protein kinase kinase · Protein kinase A · Traditional medicine · Viability assay · Antioxidant Activity and Oxidative Stress · Bioactive Compounds and Antitumor Agents · Chemistry · Medicine · Redox biology and oxidative stress · Biochemistry · Pharmacology

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