Chrysanthemum morifolium extract attenuates pathological angiogenesis of age-related macular degeneration via Vegf and Nrf2 pathway modulation

Bibliographic Data

ID14734026
AuthorsGuan-cheng Jiang (0009-0006-1059-940X), G-J Jiang (First Affiliated Hospital Zhejiang University), H Pan (0000-0002-9534-1582, Zhejiang Modern Chinese Medicine and Natural Medicine Research Institute (China)), Hong-ye Pan (Zhejiang Modern Chinese Medicine and Natural Medicine Research Institute (China)), Lei Gu (0000-0001-5119-3517), Gu Lei (First Affiliated Hospital Zhejiang University), Tian-tian Cheng, Tiantian Cheng (0000-0001-5075-2444, First Affiliated Hospital Zhejiang University), Bing-xue Zhu, Byron Zhu (First Affiliated Hospital Zhejiang University), Xiaorong Wang (0000-0001-7065-8615, First Affiliated Hospital Zhejiang University), Xuan-qi Wang (First Affiliated Hospital Zhejiang University, corresponding author), Jia-yu Yu, Jianing Yu (0000-0001-5425-3271, Zhejiang Modern Chinese Medicine and Natural Medicine Research Institute (China)), Feng Zhu (0000-0003-3663-6046, Zhejiang Modern Chinese Medicine and Natural Medicine Research Institute (China)), Ming Lin (0000-0003-0959-4290), Jiang-ning Hu, Mingwei Lin (0000-0003-2026-7178, Zhejiang Modern Chinese Medicine and Natural Medicine Research Institute (China)), Xia-wei Wang, Jiangning Hu (0000-0002-2076-4505, Zhejiang Modern Chinese Medicine and Natural Medicine Research Institute (China), corresponding author), Xiawei Wang (0009-0007-8324-2070, First Affiliated Hospital Zhejiang University)
Year2026
Volume355
IssuePt B
Pages120660
Publication date2026-01-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2025.120660
PMID41016543
OpenAlexW4414573742
LanguageEN
References cited40

CME exerts dual anti-angiogenic and antioxidant effects in AMD models by simultaneously targeting VEGF-driven angiogenesis and oxidative stress, supporting its therapeutic potential as a safe and effective herbal intervention for neovascular AMD

Angiogenesis · Antioxidant · Chrysanthemum morifolium · Macular degeneration · Neovascularization · Oxidative stress · Pathological · Corneal Surgery and Treatments · Ocular Diseases and Behçet’s Syndrome · Retinal Development and Disorders · Retinal Diseases and Treatments

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