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Cardenolides from Calotropis gigantea as potent inhibitors of hypoxia-inducible factor-1 transcriptional activity

Bibliographic Data

ID14734394
AuthorsSupawadee Parhira (0000-0002-2077-5888, Macau University of Science and Technology), Guo-Yuan Zhu, Guo‐Yuan Zhu (0000-0002-4355-894X, Macau University of Science and Technology), Ming Chen (0000-0001-6387-3739, Macau University of Science and Technology), Li-Ping Bai (0000-0002-2806-6883, Macau University of Science and Technology, corresponding author), Zhi-Hong Jiang, Zhi‐Hong Jiang (0000-0002-7956-2481, Macau University of Science and Technology, corresponding author)
Year2016
Volume194
Pages930-936
Publication date2016-12-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2016.10.070
PMID27793783
OpenAlexW2531964534
LanguageEN
Citations received2
References cited24

Bioassay · Biology · Botany · Cardenolide · Cell growth · Cytotoxicity · Gigantea · Glycoside · In vitro · MTT assay · Stereochemistry · Traditional medicine · Cancer, Hypoxia, and Metabolism · Chemistry · Marine Sponges and Natural Products · Medicine · Phytochemistry and Bioactive Compounds · Biochemistry · Pharmacology

  • Calotropis gigantea (L.) Dryand. Stem bark extract suppresses tumor angiogenesis through modulation of HIF-1α/Vegf signaling and ERK1/2-AKT activation in HepG2 xenograft-bearing nude mice

    Open Access•Aylada Kaenu, Pholawat Tingpej et al.•Journal of Ethnopharmacology•2026

  • The dichloromethane fraction from Calotropis gigantea (L.) dryand. Stem bark extract prevents liver cancer in SDT rats with insulin-independent diabetes mellitus

    Open Access•Thaiyawat Haewphet, Supawadee Parhira et al.•Journal of Ethnopharmacology•2024

Citations per year1
Citation span2024 - 2026 (3)
Highly citedNo

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