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Effects of water extract from epimedium on neuropeptide signaling in an ovariectomized osteoporosis rat model

Bibliographic Data

ID14736853
AuthorsHengrui Liu (0000-0002-5369-3926, Jinan University), Yingquan Xiong (Jinan University), Haixia Wang (0000-0001-8897-4819, Jinan University), Li Yang (0000-0003-3852-3651, Jinan University), Chaopeng Wang (Jinan University), Xiaoguang Liu (0000-0002-0176-3101, Jinan University), Zhidi Wu (Jinan University), Xiaoyun Li (0000-0002-7749-4948, Jinan University), Ling Ou (0000-0002-4437-6427, Jinan University), Ronghua Zhang (0000-0002-4758-4061, Jinan University, corresponding author), Xiaofeng Zhu (0000-0001-6840-0578, First Affiliated Hospital of Jinan University, corresponding author)
Year2018
Volume221
Pages126-136
Publication date2018-07-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2018.04.035
PMID29705515
OpenAlexW2802159203
LanguageEN
Citations received5
References cited42

The effects of osteoporosis can largely be reduced by treatment with Epimedium most likely through a mechanism associated with several neuropeptides involved in regulation of the brain/spinal cord/bone axis. These novel results contribute to existing literature regarding the possible mechanisms of habitual use of Epimedium in the treatment of osteoporosis

Bone mineral · Bone remodeling · Epimedium · Hormone · Neuropeptide · Neuropeptide Y receptor · Osteoporosis · Ovariectomized rat · Pathology · Receptor · Traditional Chinese medicine · Bone Metabolism and Diseases · Caveolin-1 and cellular processes · Medicinal Plant Pharmacodynamics Research · Medicine · Endocrinology · Internal Medicine · Pharmacology

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    Open Access•Yi Chen, Yingqi Li et al.•Journal of Ethnopharmacology•2020

  • Er-Xian decoction attenuates ovariectomy-induced osteoporosis by modulating fatty acid metabolism and IGF1/PI3K/AKT signaling pathway

    Open Access•Yujie Ma, Jing Hu et al.•Journal of Ethnopharmacology•2023

  • Metabolomics profiling reveals Echinops latifolius Tausch improves the trabecular micro-architecture of ovariectomized rats mainly via intervening amino acids and glycerophospholipids metabolism

    Open Access•Jiaqi Wang, Xin Dong et al.•Journal of Ethnopharmacology•2020

  • The genus Epimedium

    Open Access•Huiping Ma, Xirui He et al.•Journal of Ethnopharmacology•2011

Unique citing works5
Citations per year0,83
Citation span2020 - 2024 (5)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 5

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