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Er-Xian decoction attenuates ovariectomy-induced osteoporosis by modulating fatty acid metabolism and IGF1/PI3K/AKT signaling pathway

Bibliographic Data

ID14730274
AuthorsYujie Ma (0000-0001-6537-2604, Chinese Academy of Medical Sciences & Peking Union Medical College), Jing Hu (0009-0007-8446-0862, Chinese Academy of Medical Sciences & Peking Union Medical College), Changheng Song (Chinese Academy of Medical Sciences & Peking Union Medical College), Pei Li (0000-0001-9098-7598, Chinese Academy of Medical Sciences & Peking Union Medical College), Yin Cheng (0000-0001-5288-6278, Chinese Academy of Medical Sciences & Peking Union Medical College), Yuhan Wang (0009-0000-5727-0747, Chinese Academy of Medical Sciences & Peking Union Medical College), Haixia Liu (0000-0003-1047-3023, Chinese Academy of Medical Sciences & Peking Union Medical College, corresponding author), Yanjing Chen (0000-0001-9211-4993, Chinese Academy of Medical Sciences & Peking Union Medical College, corresponding author), Zhiguo Zhang (0000-0002-5081-4382, Chinese Academy of Medical Sciences & Peking Union Medical College, corresponding author)
Year2023
Volume301
Pages115835
Publication date2023-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2022.115835
PMID36252878
OpenAlexW4306181075
LanguageEN
Citations received4
References cited45

Bone remodeling · Estrogen · Lipid metabolism · Osteoclast · Osteoporosis · Ovariectomized rat · PI3K/AKT/mTOR pathway · Protein kinase B · Receptor · Signal transduction · Western blot · Bone health and osteoporosis research · Bone Metabolism and Diseases · Cancer, Lipids, and Metabolism · Chemistry · Medicine · Biochemistry · Endocrinology · Internal Medicine · Pharmacology

  • Integrating metabolomics and network pharmacology to study the mechanism of Er-Xian decoction in improving intervertebral disc degeneration

    Open Access•Xiaobo Wang, Guoqiang Ren et al.•Journal of Ethnopharmacology•2025

  • Investigating the pharmacodynamic mechanism of Erxian decoction to alleviate sarcopenia generated by ovarian aging through the ER-mediated estrogen signaling pathway

    Open Access•Fengming You, Ning Wang et al.•Journal of Ethnopharmacology•2025

  • Epimedii Folium and Curculiginis Rhizoma ameliorate age-related cognitive decline and neuroinflammation through modulation of the NLRP3 inflammasome

    Open Access•Jiaqi Ji, Bing Zhang et al.•Journal of Ethnopharmacology•2025

  • Advances in cytokine-based herbal medicine against premature ovarian insufficiency

    Open Access•Yuan Siyu, Siyu Yuan et al.•Journal of Ethnopharmacology•2024

  • Network Pharmacology Databases for Traditional Chinese Medicine

    Open Access•Runzhi Zhang, Xue Zhu et al.•Frontiers in Pharmacology•2019

  • Network pharmacology approach to elucidate possible action mechanisms of Sinomenii Caulis for treating osteoporosis

    Open Access•Wenjin Liu, Wen-jin Liu et al.•Journal of Ethnopharmacology•2020

  • Effects of water extract from epimedium on neuropeptide signaling in an ovariectomized osteoporosis rat model

    Open Access•Hengrui Liu, Yingquan Xiong et al.•Journal of Ethnopharmacology•2018

  • Curculigoside attenuates oxidative stress and osteoclastogenesis via modulating Nrf2/NF-κB signaling pathway in RAW264.7 cells

    Open Access•Mengqin Liu, Sha Liu et al.•Journal of Ethnopharmacology•2021

  • Berberine for bone regeneration

    Open Access•Yuhan Zhang, Jinlong Ma et al.•Journal of Ethnopharmacology•2021

  • Bajitianwan attenuates D-galactose-induced memory impairment and bone loss through suppression of oxidative stress in aging rat model

    Open Access•Wumu Xu, Xiaoyan Liu et al.•Journal of Ethnopharmacology•2020

  • Erxian decoction, a Chinese herbal formula, for menopausal syndrome

    Open Access•Yong Wang, Xiao-Ting Lou et al.•Journal of Ethnopharmacology•2019

  • The effects of Liuwei Dihuang on canonical Wnt/β-catenin signaling pathway in osteoporosis

    Bingjiang Xia, Bing Xu et al.•Journal of Ethnopharmacology•2014

Unique citing works4
Citations per year2
Citation span2024 - 2025 (2)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 4

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