Integrating metabolomics and network pharmacology to study the mechanism of Er-Xian decoction in improving intervertebral disc degeneration
Bibliographic Data
| ID | 14745689 |
|---|---|
| Authors | Xiaobo Wang (0000-0001-6754-7404, Ningbo Medical Center Lihuili Hospital), Guoqiang Ren (Ningbo Medical Center Lihuili Hospital), Binhui Chen (0000-0001-6540-6827, Ningbo Medical Center Lihuili Hospital, corresponding author) |
| Year | 2025 |
| Volume | 346 |
| Pages | 119702 |
| Publication date | 2025-04-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.119702 |
| PMID | 40139579 |
| OpenAlex | W4408840082 |
| Language | EN |
| References cited | 42 |
Biological activity · Biology · Decoction · Degeneration (medical · In vitro · Intervertebral disc · Mechanism (biology · Pathology · Pharmacognosy · Traditional medicine · Healthcare and Venom Research · Medical Imaging and Analysis · Medicine · Philosophy · Spine and Intervertebral Disc Pathology · Anatomy · Biochemistry · Pharmacology
The GeneCards Suite
Kegg
Water extract of Er-xian decoction selectively exerts estrogenic activities and interacts with Serms in estrogen-sensitive tissues
Er-Xian decoction attenuates ovariectomy-induced osteoporosis by modulating fatty acid metabolism and IGF1/PI3K/AKT signaling pathway
Uncovering the mechanisms of Zhubi decoction against rheumatoid arthritis through an integrated study of network pharmacology, metabolomics, and intestinal flora
| Citation velocity | historical |
|---|---|
| Highly cited | No |