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Toxicological evaluation of Artocarpus lacucha ethyl acetate extract

In vitro and in vivo assessment

Bibliographic Data

ID14738433
AuthorsTanmoy Banerjee (0000-0002-1701-501X, Jadavpur University), Arnab Sarkar (0000-0002-7354-2092, Jadavpur University), Akash De (Jadavpur University), Shuvam Sar (0009-0004-2321-9467, Jadavpur University), Avishek Mandal (Jadavpur University), Parthasarathi Panda (0000-0003-0071-708X, MCPHS University), Amit Kumar Halder (0000-0002-4818-9047, CDA College), Sanmoy Karmakar (0000-0003-2162-5061, Jadavpur University), Nilanjan Ghosh (0000-0002-7217-243X, Jadavpur University, corresponding author)
Year2025
Volume347
Pages119804
Publication date2025-05-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2025.119804
PMID40228589
OpenAlexW4409387557
LanguageEN
Citations received2
References cited53

The findings demonstrated that AL-EAE did not possess cytotoxicity in vitro. In both acute and subacute toxicity studies, AL-EAE was shown to be nontoxic, where 400 mg/kg/day was the no-observed-adverse-effect level (NOAEL) dosage in rodents

Biological activity · Biology · Chromatography · Ethyl acetate · In vitro · In vivo · Moraceae · Pharmacognosy · Traditional medicine · Bioactive natural compounds · Chemistry · Medicine · Natural product bioactivities and synthesis · Ziziphus Jujuba Studies and Applications · Biochemistry · Biotechnology · Pharmacology

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    Open Access•Vinícius de C Oliveira, Sarah de O Rodrigues et al.•Journal of Ethnopharmacology•2024

  • Zanthoxylum armatum DC fruit ethyl acetate extract site induced hepatotoxicity by activating endoplasmic reticulum stress and inhibiting autophagy in BRL-3A models

    Open Access•Jian Zhang, Jiafu Guo et al.•Journal of Ethnopharmacology•2024

  • Ethanolic extract of Cordyceps cicadae exerts antitumor effect on human gastric cancer SGC-7901 cells by inducing apoptosis, cell cycle arrest and endoplasmic reticulum stress

    Open Access•Hongqing Xie, Xiaotong Li et al.•Journal of Ethnopharmacology•2019

  • Artocarpus

    Open Access•Umesh B Jagtap, Vishwas A Bapat•Journal of Ethnopharmacology•2010

  • Neurotoxicity study of ethyl acetate extract of Zanthoxylum armatum DC. on SH-SY5Y based on ROS mediated mitochondrial apoptosis pathway

    Open Access•Jiafu Guo, Nannan Yang et al.•Journal of Ethnopharmacology•2024

Unique citing works2
Citations per year2
Citation span2026 - 2027 (2)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 1

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