Multi-targeted action of rooibos may protect against ischaemic stroke-induced neurological deficit and endothelial dysfunction

Bibliographic Data

ID14738693
AuthorsL Pretorius (0000-0001-9906-9785, Stellenbosch University), K S Ross (0000-0003-2887-6568, Stellenbosch University), Carine Smith (0000-0001-5924-9204, Stellenbosch University, corresponding author)
Year2025
Volume337
IssuePt 1
Pages118822
Publication date2025-01-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2024.118822
PMID39260709
OpenAlexW4402390458
LanguageEN
References cited39

Taken together, activity data and physiological assessments suggest that unfermented rooibos may indeed have benefit in the context of stroke, via action at multiple targets. Thus, current data further our understanding of the mechanisms of actions of rooibos and warrant future research to confirm sufficient bioavailability of rooibos in target tissues, in mammalian systems

Antioxidant · Biology · Blood pressure · Endothelial Dysfunction · Neuroprotection · Stroke (engine · Traditional medicine · Eicosanoids and Hypertension Pharmacology · Inflammatory mediators and NSAID effects · Medicine · Neurological Disease Mechanisms and Treatments · Internal Medicine · Pharmacology

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