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The effects and mechanisms of chai shao jie yu granules on chronic unpredictable mild stress (Cums)-induced depressive rats based on network pharmacology

Datos Bibliográficos

ID14740467
AutoresQin Tang (0000-0001-9296-4074, Beijing University of Chinese Medicine), Haolin Chu (0009-0007-7303-0541, Beijing University of Chinese Medicine), Nan Sun (0000-0001-7583-9802, Beijing University of Chinese Medicine), Xiaoxu Fan (0000-0002-6487-3797, Beijing University of Chinese Medicine), Bing Han (0000-0003-2804-928X, Education Department of Heilongjiang Province), Yu Li (0000-0002-0964-6399, Chinese Academy of Medical Sciences & Peking Union Medical College), Xue Yu (0000-0002-7703-0764, Beijing University of Chinese Medicine), Lina Li (0000-0003-1484-5883, Beijing University of Chinese Medicine), Xiuli Wang (0000-0002-0754-177X, Beijing University of Chinese Medicine), Liying Liu (0000-0002-0637-7488, Education Department of Heilongjiang Province, autor de correspondencia), Hongsheng Chang (0000-0003-1699-5551, Beijing University of Chinese Medicine, autor de correspondencia)
Año2025
Volumen340
Páginas119268
Fecha de publicación2025-01-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Ethnopharmacology (JOURNAL)
Identificadores de la revistaISSN: 0378-8741 • E-ISSN: 1872-7573
EditorialElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2024.119268
PMID39706355
OpenAlexW4405531723
IdiomaEN
Citas recibidas3
Referencias citadas82

CSJY demonstrated the ability to alleviate depressive behaviors in CUMS-induced depression rats, potentially through the inhibition of the hypothalamic-pituitary-adrenal (HPA) axis, modulation of monoamine neurotransmitters, and glutamatergic neurons. These findings suggest that CSJY could serve as a promising treatment option for depression

Biological activity · Chai · Chronic stress · In vitro · Pharmacognosy · Traditional medicine · Chemistry · Medicine · Metabolomics and Mass Spectrometry Studies · Pharmacological Effects of Natural Compounds · Philosophy · Tryptophan and brain disorders · Biochemistry · Internal Medicine · Pharmacology

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Obras citantes distintas3
Citas por año3
Intervalo de citas2025 - 2026 (2)
Velocidad de citacióncurrent
Altamente citadoNo
Tipos de citaNeutras: 3
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