Induction of EpRE-mediated gene expression by a series of mediterranean botanicals and their constituents

Bibliographic Data

ID14741195
AuthorsGeorgia Papadi (0000-0002-6081-0748, University of Ioannina, corresponding author), Sebastiaan Wesseling (0000-0002-8162-1030, Wageningen University & Research), Anastassios N Troganis (0000-0002-7794-542X, University of Ioannina), Jacques Vervoort (0000-0002-0091-5687, Wageningen University & Research), Ivonne M C M Rietjens (0000-0003-1894-3544, Wageningen University & Research)
Year2019
Volume240
Pages111940
Publication date2019-08-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2019.111940
PMID31071423
OpenAlexW2944213497
LanguageEN
References cited122

The protective effect of half of the tested botanical varieties via the activation of EpRE-mediated gene expression was confirmed. The study also provided an example of how in vitro bioassays can be combined with LC-MS and the automated chemical annotation software MAGMa, to identify biologically active constituents in complex botanical extracts

Biological activity · Biology · Emodin · Gene · Gene expression · In silico · In vitro · Reporter gene · Antioxidant Activity and Oxidative Stress · Chemistry · Genomics, phytochemicals, and oxidative stress · Phytochemicals and Antioxidant Activities · Biochemistry

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