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Sijunzi decoction alleviates cancer cachexia myatrophy by suppressing M2 polarization of tumor-associated macrophages via the MCT1/lactate/H3K18 lactylation pathway

Bibliographic Data

ID14747009
AuthorsDengyun Nie (0000-0001-6622-7513, Nanjing University of Chinese Medicine), Yakun Zhang (0000-0001-6622-5016, Nanjing University of Chinese Medicine), Rong Jia (0000-0002-5306-5241, Nanjing University of Chinese Medicine), Zhe Fang (0000-0003-0864-3644, Nanjing University of Chinese Medicine), Guisong Zhu (0000-0003-2036-7531, Nanjing University of Chinese Medicine), Biao Xu (0000-0001-8695-7396, Nanjing University of Chinese Medicine), Ting Guo (0000-0001-7537-2464, Nantong University, corresponding author), Han Chao Zhang (Nanjing University of Chinese Medicine, corresponding author), Han Zhang (0000-0002-5265-7659, Nanjing University of Chinese Medicine, corresponding author)
Year2026
Volume364
Pages121500
Publication date2026-06-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2026.121500
PMID41796614
OpenAlexW7134112581
LanguageEN
References cited25

Cachexia · Cancer · Cancer cachexia · Cell culture · Decoction · In vitro · Macrophage polarization · Antioxidants, Aging, Portulaca oleracea · Immune cells in cancer · Nutrition and Health in Aging

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