Risk factors for intensive care unit admission and death from Covid-19 in fully vaccinated patients hospitalized for severe Covid-19, Brazil, 2021–2022
Bibliographic Data
| ID | 14967117 |
|---|---|
| Authors | Gbènankpon Mathias Houvèssou (0000-0003-3401-2547, Universidade Federal de Pelotas, corresponding author), Pedro C G Vargas (Universidade Federal de Pelotas), Pedro Vargas (0000-0002-2114-6856, Universidade Federal de Pelotas), Nadège Jacques (0000-0002-2204-3330, Center for Haitian Studies, Miami FL, United States of America), Daniel G P Leventhal (0000-0001-5229-5697, Universidade Federal de Pelotas) |
| Year | 2022 |
| Volume | 46 |
| Pages | 1 |
| Publication date | 2022-11-18 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Revista Panamericana de Salud Pública (JOURNAL) |
| Journal identifiers | ISSN: 1020-4989 • E-ISSN: 1680-5348 |
| Publisher | Pan American Health Organization (PUBLISHER • US) |
| DOI | 10.26633/rpsp.2022.203 |
| PMID | 36415786 |
| OpenAlex | W4309464995 |
| Language | EN |
| References cited | 25 |
Objectives. To assess factors associated with admission to an intensive care unit (ICU) and death from coronavirus disease 2019 (COVID-19) in fully vaccinated patients with severe COVID-19 in Brazil and the association between ICU admission and death from COVID-19. Methods. This was retrospective study of patients hospitalized for COVID-19 from February 12, 2021 to January 10, 2022 across Brazil who were fully vaccinated against COVID-19 before hospitalization. Outcomes were admission in an ICU for COVID-19 and death from COVID-19. Variables evaluated were: sex; age; self-reported skin color; macroregion; comorbidities; time between full vaccination and onset of symptoms; and time between onset of symptoms and hospitalization. A Poisson regression model was used to estimate crude and adjusted risk ratios. Results. Of 74 991 patients hospitalized for severe COVID-19, 67.28% were ≥ 70 years and 68.32% had at least one comorbidity. Men, patients aged 60–69 years, and patients aged 18–39 years with obesity had the greatest risk of ICU admission. Patients aged 18–39 years with obesity, diabetes, or renal diseases had the highest risk of death from COVID-19. When age and time between onset of symptoms and hospitalization were considered effect modifiers, patients admitted to an ICU 9–13 days after symptom onset in each age category had the greatest risk of death from COVID-19. Conclusion. Although older patients were at greatest risk of ICU admission and death from COVID-19, the difference in the risk of dying from COVID-19 between patients admitted to an ICU and those not admitted was greatest for young adults
Comorbidity · Coronavirus disease 2019 (COVID-19 · Diabetes mellitus · Disease · Infectious disease (medical specialty · Intensive care unit · Poisson regression · Population · Retrospective cohort study · COVID-19 Clinical Research Studies · COVID-19 epidemiological studies · Medicine · SARS-CoV-2 and COVID-19 Research · Emergency Medicine · Internal Medicine · Pediatrics
Impact of sex and gender on Covid-19 outcomes in Europe
The species Severe acute respiratory syndrome-related coronavirus
Efficacy and Safety of the mRNA-1273 Sars-CoV-2 Vaccine
Risk factors for severe and critically ill Covid‐19 patients
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China
Characterisation of the first 250 000 hospital admissions for Covid-19 in Brazil
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
Clinical course and risk factors for mortality of adult inpatients with Covid-19 in Wuhan, China
Gender Differences in Patients With Covid-19
Obesity and Covid-19 in-hospital fatality in southern Brazil
| Highly cited | No |
|---|