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Costa Rica’s trans-fat ban impact on cardiovascular disease

A macrosimulation study

Bibliographic Data

ID14968181
AuthorsRafael Monge-Rojas (0000-0001-7660-2508, Health and Nutrition Unit, Costa Rican Institute for Research and Education on Nutrition and Heath, Tres Rios, Cartago, Costa Rica., corresponding author), Rulamán Vargas-Quesada (0000-0002-5944-3071, Health and Nutrition Unit, Costa Rican Institute for Research and Education on Nutrition and Heath, Tres Rios, Cartago, Costa Rica.), Victor Villalobos-Daniel (Pan American Health Organization, Washington, DC, USA.), Victor E Villalobos-Daniel (0000-0003-1112-8643, World Health Organization Regional Office for the Americas), Eduardo Augusto Fernandes Nilson (0000-0002-2650-4878, Oswaldo Cruz Foundation–Fiocruz, Brasilia, Brazil.)
Year2025
Volume49
Pages1
Publication date2025-10-10
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueRevista Panamericana de Salud Pública (JOURNAL)
Journal identifiersISSN: 1020-4989 • E-ISSN: 1680-5348
PublisherPan American Health Organization (PUBLISHER • US)
DOI10.26633/rpsp.2025.97
PMID41079056
OpenAlexW4415030796
LanguageEN
References cited34

Objective: This study uses a modeling framework to assess the potential impact of implementing the World Health Organization (WHO) REPLACE strategy to reduce the intake of industrially produced trans-fatty acids (IP-TFAs) on cardiovascular disease (CVD) in Costa Rica. Methods: The TFA Macrosimulation Model was used to estimate reductions in CVD mortality under three regulatory scenarios: (1) setting IP-TFA limits at 2% in oils and fats and 5% in other foods; (2) applying a uniform 2% IP-TFA limit across all foods; and (3) implementing a complete ban on partially hydrogenated oils (PHOs). Results: The model estimates that enforcing a 2% IP-TFA limit across all foods could prevent or delay approximately 128 deaths annually (3.0% of CVD mortality), while a full PHO ban could avert about 215 deaths per year (5.0% of CVD mortality). Economically, the PHO ban could yield annual savings of approximately US$2.1 million by reducing productivity losses associated with premature mortality. Conclusion: Implementing the WHO REPLACE strategy has the potential to substantially reduce CVD mortality, while also improving the population’s health and economic productivity. These findings offer strong evidence to advocate for regulatory actions in Costa Rica and other nations across the Americas region to eliminate IP-TFAs from the food supply

Disease · Food security · Government (linguistics · Investment (military · Legislation · Public health · Consumer Attitudes and Food Labeling · Fatty Acid Research and Health · Global Public Health Policies and Epidemiology

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