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Determinants of low birth weight in urban Pakistan

Bibliographic Data

ID15091119
AuthorsNaveed Z Janjua (0000-0001-5681-719X, Aga Khan University, corresponding author), Elizabeth Delzell (University of Alabama at Birmingham), Rodney R Larson (University of Utah), Sreelatha Meleth (0000-0001-7149-8262, University of Alabama at Birmingham), Sibylle Kristensen (University of Alabama at Birmingham), Edmond K Kabagambe (0000-0002-8993-3186, University of Alabama at Birmingham), Edmond Kabagambe, Nalini Sathiakumar (University of Alabama at Birmingham)
Year2009
Volume12
Issue6
Pages789-798
Publication date2009-06-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980008002942
PMID18620611
OpenAlexW2010742867
LanguageEN
Citations received8
References cited38

Objective To identify determinants of low birth weight (LBW) in Karachi, Pakistan, including environmental exposures and nutritional status of the mother during pregnancy. Design Cross-sectional study. Participants Five hundred and forty mother–infant pairs. We interviewed mothers about obstetric history, diet and exposure to Pb. We measured birth weight and blood lead level (BLL). We performed multiple log binomial regression analysis to identify factors related to LBW. Results Of 540 infants, 100 (18·5 %) weighed ≤2·5 kg. Umbilical cord BLL was not significantly associated with LBW. Maternal poor self-rated health (adjusted prevalence ratio (adjPR) = 1·83; 95 % CI 1·09, 3·07) and none or one prenatal visit (adjPR = 2·18; 95 % CI 1·39, 3·43) were associated with LBW. A statistically significant interaction between mothers’ mid upper-arm circumference (MUAC) and dietary vitamin C intake was noted. Compared with mothers with MUAC above the median and dietary vitamin C intake above the 3rd quartile (>208·7 mg/d), infants of mothers with MUAC less than or equal to the median and dietary vitamin C intake >208·7 mg/d (adjPR = 10·80; 95 % CI 1·46, 79·76), mothers with MUAC above the median and vitamin C intake ≤208.7 mg/d (adjPR = 10·67; 95 % CI 1·50, 76·02) and mothers with MUAC less than or equal to the median and vitamin C intake ≤208·7 mg/d (adjPR = 13·19; 95 % CI 1·85, 93·79) more likely to give birth to an LBW infant. Conclusions In Pakistan, poor nutritional status and inadequate prenatal care were major determinants of LBW in this setting. Environmental factors including umbilical cord BLL were not significantly associated with LBW

Anthropometry · Birth weight · Confidence interval · Cross-sectional study · Low birth weight · Obstetrics · Pregnancy · Quartile · Vitamin D and neurology · Birth, Development, and Health · Demography · Gestational Diabetes Research and Management · Health disparities and outcomes · Medicine · Internal Medicine · Pediatrics

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Unique citing works8
Citations per year0,47
Citation span2009 - 2022 (14)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 8

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