Legume consumption and its association with fasting glucose, insulin resistance and type 2 diabetes in the Indian Migration Study

Bibliographic Data

ID15092118
AuthorsPreet K Dhillon (0000-0002-0291-9454, Public Health Foundation of India, corresponding author), Liza Bowen (0000-0001-8318-8421, London School of Hygiene & Tropical Medicine), Sanjay Kinra (0000-0001-6690-4625, London School of Hygiene & Tropical Medicine), Ankalmadugu Venkatsubbareddy Bharathi, A Bharathi, Sutapa Agrawal (0000-0001-8088-2143, Public Health Foundation of India), Dorairaj Prabhakaran (0000-0002-3172-834X, Public Health Foundation of India), K Srinath Reddy (0000-0003-3416-3548, Public Health Foundation of India), Shah Ebrahim (0000-0001-9438-1438, London School of Hygiene & Tropical Medicine)
Year2016
Volume19
Issue16
Pages3017-3026
Publication date2016-11-01
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980016001233
PMID27329792
OpenAlexW2467146708
LanguageEN
Citations received1
References cited62

Objective Legume consumption is associated with lower fasting glucose (FG) and insulin levels in nutrition trials and lower CVD mortality in large-scale epidemiological studies. In India, legumes are widely consumed in various preparations, yet no epidemiological study has evaluated the association of legumes with FG levels, insulin resistance and diabetes risk. The present study aimed to fill this gap. Design Fasting blood samples, in-person interviews to obtain information on demographic/socio-economic factors, physical activity, alcohol and tobacco use, and anthropometric measurements were collected. Dietary intakes were assessed by an interviewer-administered, validated, semi-quantitative FFQ. Setting Lucknow, Nagpur, Hyderabad and Bangalore, India. Subjects Men and women ( n 6367) aged 15–76 years – urban residents, urban migrants and their rural siblings. Results In multivariate random-effects models adjusted for age, BMI, total energy intake, macronutrients, physical activity and rural/migration status, daily legume consumption was not associated with FG ( P -for-trend=0·78), insulin resistance (homeostasis model assessment score; P -for-trend=0·73) or the prevalence of type 2 diabetes mellitus ( P -for-trend=0·41). Stratified analyses by vegetarian diet and migration status did not change the findings. Inverse associations between legumes and FG emerged for participants with lower BMI and higher carbohydrate, protein, fat and sugar intakes. Conclusions Although legumes are essential in traditional Indian diets, as well as in prudent and Mediterranean diets in the West, we did not find an association between legumes and markers of glycaemic control, insulin resistance or diabetes, except for subgroups based on BMI and macronutrient intake. The ubiquitous presence and complexity of legume preparations in Indian diets may contribute to these findings

Agronomy · Association (psychology · Biology · Consumption (sociology · Diabetes mellitus · Fasting glucose · Insulin · Insulin resistance · Legume · Sociology · Type 2 diabetes · Medicine · Nutritional Studies and Diet · Obesity, Physical Activity, Diet · Phytoestrogen effects and research · Psychology · Endocrinology · Internal Medicine

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